Detailed information NTG0215486

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: CV725_RS07155
• Genome accession: NZ_CP024951
• Coordinates: 1457649..1460225 (+)
• Length: 858 a.a.
• NCBI ID: WP_000893946.1
• Uniprot ID: -
• Organism: Helicobacter pylori B128
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1452649..1465225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CV725_RS07115 (CV725_07130)	-	1453605..1454678 (+)	1074	WP_001278345.1	site-specific integrase	-
CV725_RS07120 (CV725_07135)	-	1454758..1455423 (-)	666	WP_041201762.1	hypothetical protein	-
CV725_RS07125 (CV725_07140)	-	1455473..1456261 (+)	789	WP_001140571.1	hypothetical protein	-
CV725_RS07130 (CV725_07145)	-	1456264..1456494 (+)	231	WP_000189079.1	hypothetical protein	-
CV725_RS07135 (CV725_07150)	-	1456487..1456864 (+)	378	WP_000571141.1	hypothetical protein	-
CV725_RS07140 (CV725_07155)	comB2	1456842..1457126 (+)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
CV725_RS07145 (CV725_07160)	comB3	1457138..1457401 (+)	264	WP_001177716.1	hypothetical protein	Machinery gene
CV725_RS07150 (CV725_07165)	-	1457413..1457649 (+)	237	WP_001168532.1	hypothetical protein	-
CV725_RS07155 (CV725_07170)	comB4	1457649..1460225 (+)	2577	WP_000893946.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
CV725_RS08515 (CV725_07175)	-	1460222..1460362 (+)	141	WP_000789929.1	hypothetical protein	-
CV725_RS07165 (CV725_07180)	-	1460355..1461491 (+)	1137	WP_000067692.1	VirB8/TrbF family protein	-
CV725_RS07170 (CV725_07185)	-	1461488..1463143 (+)	1656	WP_000617227.1	TrbG/VirB9 family P-type conjugative transfer protein	-
CV725_RS07175 (CV725_07190)	comB10	1463140..1464348 (+)	1209	WP_000814183.1	DNA type IV secretion system protein ComB10	Machinery gene

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 98534.67 Da
• Isoelectric Point: 8.8751

>NTDB_id=215486 CV725_RS07155 WP_000893946.1 1457649..1460225(+) (comB4) [Helicobacter pylori B128]
MLESALKYCKEKAIDLLAGFVPKTYSMAQECNILGLYDDTFIITKQENLVGIISLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNIYAKAIITQFESKEIYKTEYFLVFETITSNVKSFFEKKKLEMTTSINEELEES
SKEDKQENENSSNETHSNTSSKKDKKNKFKKKITFSATSKRALLIQTIERVKNALKEFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNVHFKKDYFVIEFQNQNTFCACVGIKAYESEEISSIPISTLLHTKIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKADIDNYIELVQANRLSMQECALNLVIRAKSKAKLDKSLKEILSLLNNAGLGSVAETIGLKPSYF
SFFPNNANINPRMRHQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYSNIDILALDRLNGLYSFTKYFDGIYNQGENFHINPFSLEDSATNRAFLLHFYAQM
AKVDSYDDHKDKVEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNAIVKTNADILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALRINRGFLCFIDEFKSYAQNEIMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIDNLIKHYPKTWREVFVSNKHENFDDKKHLEKVLK

Nucleotide

• Length: 2577 bp

>NTDB_id=215486 CV725_RS07155 WP_000893946.1 1457649..1460225(+) (comB4) [Helicobacter pylori B128]
ATGTTAGAAAGCGCCCTTAAATATTGCAAGGAAAAAGCCATAGACCTTTTAGCAGGGTTTGTGCCAAAAACCTATTCTAT
GGCACAGGAGTGCAATATTTTAGGCTTGTATGATGATACTTTCATTATTACCAAACAAGAAAATCTAGTAGGCATTATAT
CCTTACAAGGACTAAGCTATTCTAATTTAATGCAAAAAGACTTAGAGGGCTATTTTGATACTAGACAAAATGTTCTCAAC
ACCATTAGTAAAGACATTCAATTAAGAATTGTGGCTAAAAGGCGTAAGGAATTTATCAATCAAAGTCCAAATATTGACAA
TATTTATGCCAAAGCTATTATCACACAATTTGAAAGCAAGGAAATCTATAAAACAGAGTATTTTTTAGTGTTTGAAACTA
TCACTTCTAATGTCAAGTCTTTCTTTGAAAAAAAGAAATTGGAAATGACTACTTCAATTAATGAAGAGTTAGAAGAAAGC
TCTAAAGAAGATAAACAAGAGAATGAAAATAGCTCCAATGAAACTCATTCAAACACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGATAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTAAAAAACG
CTCTTAAAGAATTTAAACCCACTTTACTAAATTCTAAAGAAGTATTAAATTTCTACGCAGAATACATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGATTAAGCGATAGCTATATTGCATCTAATGTGCATTTTAAGAAAGATTACTTTGT
CATTGAATTTCAAAATCAAAACACCTTTTGTGCGTGTGTGGGGATTAAGGCTTATGAGAGCGAAGAAATTTCTTCGATCC
CTATATCTACTCTTTTACACACCAAAATTGAACTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCCTG
AATTTTTTAAAAACTAAGAAAAAGCTCACGCTTTCTAAAATAGTAAAAGCTGATATTGATAATTATATAGAATTAGTGCA
AGCCAATCGTTTGAGCATGCAAGAGTGTGCTTTAAACTTAGTTATAAGGGCTAAAAGTAAAGCTAAATTAGACAAGTCTT
TAAAAGAGATTTTATCCTTGCTTAATAATGCTGGACTAGGCAGTGTTGCAGAAACTATAGGGCTAAAACCATCTTATTTT
TCATTCTTCCCAAATAACGCCAATATCAACCCTAGAATGAGACATCAAACTTCCCAAGTCATAGCATCTTTGATTTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCTTGGGGGGATATGCCCTTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAATTTTCATAATCAAGAAGTCAAACATAAGGGCGTGTTAGCCCACAATGTCGCACGAGTAGTGGGACAT
ACCATGATTATAGGAGCAACAGGTGCTGGTAAAACCACACTCATTAGCTATTTGATGATGAGTGCCTTAAAATATTCTAA
CATTGATATTTTAGCTCTTGATAGACTAAATGGTTTGTATTCCTTTACCAAGTATTTTGATGGGATTTATAATCAAGGCG
AAAACTTTCATATTAACCCTTTTTCATTAGAAGATAGCGCAACTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTGGATAGTTATGATGACCATAAGGATAAAGTAGAAGATAGAACAGCCCTTTTAAATGCTATTGATACGATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCCCTTCCTTTTGATTTAAAAGAGTTTG
TCAATGCCATTGTTAAAACCAATGCAGACATTTTAGATAGTAGTTTTGAAGACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGTCTAGATTTTAAAACTCGTATTAGCACCATAAATACCGATAGCATTTTACATAATGATGATGACGCTGG
GCTTTTAGCCTACTATGTCTTTCATAAGATGATTGACAGAGCCTTAAGAATCAATCGTGGGTTTTTATGCTTTATTGATG
AGTTTAAGTCTTACGCTCAAAATGAAATAATGAATAAAAAAATCAATGAAATCATTACTCAAGCTAGAAAGGCTAATGGG
GTGATTGTTCTAGCCTTACAAGACATTAACCAACTAAGCGAAGTGAGAAACGCTCAAAGCTTTATAAAAAATATGGGGCA
ATTGATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTAAGTTCTTTGGGTAATTACCTACAAATCTTTAGCTCTAATTCTAGCATGGTAGAACACATTGATAATCT
CATTAAGCATTACCCTAAAACTTGGCGAGAAGTCTTTGTGAGTAACAAACACGAAAATTTTGATGACAAAAAACACTTAG
AAAAGGTGCTTAAATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-505)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.786	97.902	0.458