Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   SPY_RS04220 Genome accession   NC_002737
Coordinates   821197..821673 (+) Length   158 a.a.
NCBI ID   WP_010922230.1    Uniprot ID   -
Organism   Streptococcus pyogenes M1 GAS     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 816197..826673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPY_RS04190 (SPy1001) - 816360..816971 (+) 612 WP_002990014.1 DUF1366 domain-containing protein -
  SPY_RS04195 (SPy1002) - 816982..817278 (+) 297 WP_002990012.1 hypothetical protein -
  SPY_RS04200 - 817275..817460 (+) 186 WP_078237818.1 hypothetical protein -
  SPY_RS04205 (SPy1006) - 817572..818906 (+) 1335 WP_010922227.1 GH25 family lysozyme -
  SPY_RS04210 (SPy1007) spei 819180..819857 (+) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  SPY_RS04215 (SPy1008) speh 819883..820593 (+) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  SPY_RS04220 (SPy1010) mutX 821197..821673 (+) 477 WP_010922230.1 NUDIX hydrolase Machinery gene
  SPY_RS04225 (SPy1011) - 821731..822912 (+) 1182 WP_002990002.1 AI-2E family transporter -
  SPY_RS04230 (SPy1012) - 822902..824149 (+) 1248 WP_010922231.1 tetratricopeptide repeat protein -
  SPY_RS04235 (SPy1013) fbp54 824208..825860 (-) 1653 WP_010922232.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18452.64 Da        Isoelectric Point: 4.3268

>NTDB_id=21542 SPY_RS04220 WP_010922230.1 821197..821673(+) (mutX) [Streptococcus pyogenes M1 GAS]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=21542 SPY_RS04220 WP_010922230.1 821197..821673(+) (mutX) [Streptococcus pyogenes M1 GAS]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTTCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

69.62

100

0.696

Multiple sequence alignment