Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   SERP_RS12230 Genome accession   NC_002976
Coordinates   2557297..2558646 (+) Length   449 a.a.
NCBI ID   WP_000815654.1    Uniprot ID   Q4JFB2
Organism   Staphylococcus epidermidis RP62A     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2552297..2563646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SERP_RS13650 (SERP2493) - 2552343..2553484 (+) 1142 Protein_2364 IS3-like element ISSau4 family transposase -
  SERP_RS12215 (SE2494) - 2553735..2554781 (+) 1047 WP_001060127.1 hypothetical protein -
  SERP_RS12220 (SE2495) - 2554974..2555270 (+) 297 WP_000273824.1 cassette chromosome ssDNA-binding protein -
  SERP_RS12225 (SE2496) - 2555270..2557063 (+) 1794 WP_000195102.1 cassette chromosome replicative helicase -
  SERP_RS12230 (SE2498) ccrA 2557297..2558646 (+) 1350 WP_000815654.1 cassette chromosome recombinase CcrA Machinery gene
  SERP_RS12235 (SE2499) ccrB 2558668..2560296 (+) 1629 WP_001186599.1 cassette chromosome recombinase CcrB Machinery gene
  SERP_RS12240 (SE2501) - 2560814..2561164 (+) 351 WP_000859155.1 SAUGI family uracil-DNA glycosylase inhibitor -
  SERP_RS12245 (SE2503) - 2561251..2561562 (+) 312 WP_000700853.1 DUF960 family protein -
  SERP_RS12250 (SE2504) - 2561580..2562086 (+) 507 WP_001092169.1 DUF1643 domain-containing protein -
  SERP_RS12255 (SE2505) - 2562107..2562424 (+) 318 WP_000659050.1 JAB domain-containing protein -
  SERP_RS12260 (SE2506) - 2562543..2563628 (+) 1086 WP_000868132.1 tyrosine-type recombinase/integrase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52665.36 Da        Isoelectric Point: 10.0809

>NTDB_id=21431 SERP_RS12230 WP_000815654.1 2557297..2558646(+) (ccrA) [Staphylococcus epidermidis RP62A]
MKQVIGYLRQSTMKQQSLAAQKQAIEAITEKHHIQHINFYSDKQSGRKDNRSGYRQITQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTPSDNQLKQKIKCPCCNATLTNMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CRDFYQNQRIYTKIKSAIDKRIKRQRNIEKHHTLTQKQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQNTIQ
NIIQKRFTLNMLYPYIDEILITKSKTLMGIYFKNEPLNIVNQTTQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=21431 SERP_RS12230 WP_000815654.1 2557297..2558646(+) (ccrA) [Staphylococcus epidermidis RP62A]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAACCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATAACACAATTAATTCAACAAGGACAGTGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGTGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATTATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGTCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACACCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCATTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAAGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAAAACAACTGATAGAAAAGTTGGCACAAGGCATCATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGGCATCAAATACAAAACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATGCTGTATCCCTACATTGATGAAATTCTTATCACAAAAAGTAAAACACT
AATGGGTATCTATTTCAAAAATGAACCCTTAAACATCGTCAATCAAACAACGCAATCGTCAATTGCATAA

Domains

Predicted by InterProScan.

Recombinase (Recombinase)

(169-248)

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

95.323

100

0.953
  ccrA Staphylococcus aureus COL

75.501

100

0.755

Multiple sequence alignment