Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SAS_RS10540 Genome accession   NC_002953
Coordinates   2089217..2089933 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus subsp. aureus MSSA476     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2084217..2094933
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SAS_RS10510 (SAS1939) - 2084433..2085059 (+) 627 WP_000522384.1 nitroreductase family protein -
  SAS_RS10515 (SAS1940) - 2085420..2086205 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  SAS_RS15330 hld 2086804..2086884 (-) 81 WP_000046023.1 delta-hemolysin -
  SAS_RS10525 (SAS1941) - 2087174..2087737 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  SAS_RS10530 (SAS1942) agrD 2087741..2087881 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  SAS_RS10535 (SAS1943) agrC 2087906..2089198 (+) 1293 WP_000387808.1 quorum-sensing sensor histidine kinase AgrC -
  SAS_RS10540 (SAS1944) agrA 2089217..2089933 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  SAS_RS10545 - 2090005..2090114 (+) 110 Protein_2000 hypothetical protein -
  SAS_RS10550 (SAS1945) - 2090302..2091261 (-) 960 WP_001253302.1 carbohydrate kinase family protein -
  SAS_RS10555 (SAS1946) - 2091258..2092742 (-) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  SAS_RS10560 (SAS1947) - 2092891..2093841 (-) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=21334 SAS_RS10540 WP_000688492.1 2089217..2089933(+) (agrA) [Staphylococcus aureus subsp. aureus MSSA476]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=21334 SAS_RS10540 WP_000688492.1 2089217..2089933(+) (agrA) [Staphylococcus aureus subsp. aureus MSSA476]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment