Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   LB080_RS09035 Genome accession   NZ_CP019120
Coordinates   1704386..1706188 (+) Length   600 a.a.
NCBI ID   WP_076026612.1    Uniprot ID   -
Organism   Lactobacillus delbrueckii subsp. bulgaricus strain DSM 20080     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1688315..1727002 1704386..1706188 within 0


Gene organization within MGE regions


Location: 1688315..1727002
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LB080_RS08950 (LB080_08955) - 1688315..1689094 (-) 780 WP_076026605.1 C40 family peptidase -
  LB080_RS08955 (LB080_08960) - 1689140..1689847 (-) 708 WP_076026606.1 C40 family peptidase -
  LB080_RS08960 (LB080_08965) - 1690001..1690783 (-) 783 WP_076026607.1 C40 family peptidase -
  LB080_RS08965 (LB080_08970) - 1690972..1691445 (-) 474 WP_014565355.1 C40 family peptidase -
  LB080_RS08970 (LB080_08975) - 1691615..1692661 (-) 1047 WP_011544283.1 2-hydroxyacid dehydrogenase -
  LB080_RS08975 (LB080_08980) - 1692945..1693430 (-) 486 WP_003621166.1 C40 family peptidase -
  LB080_RS08980 (LB080_08985) - 1693555..1694097 (-) 543 WP_014565358.1 guanylate kinase -
  LB080_RS08985 (LB080_08990) - 1694204..1694539 (+) 336 WP_003621162.1 DUF2187 domain-containing protein -
  LB080_RS08990 (LB080_08995) - 1694603..1696165 (+) 1563 WP_076026608.1 O-antigen ligase family protein -
  LB080_RS08995 (LB080_09000) - 1696198..1696824 (-) 627 WP_076026609.1 LVIS_2131 family protein -
  LB080_RS09000 (LB080_09005) - 1696827..1697342 (-) 516 WP_003621156.1 hypothetical protein -
  LB080_RS09005 (LB080_09010) - 1697929..1698420 (-) 492 WP_014565360.1 threonine/serine exporter family protein -
  LB080_RS09010 (LB080_09015) - 1698423..1699178 (-) 756 WP_003621153.1 threonine/serine exporter family protein -
  LB080_RS09015 (LB080_09020) - 1699231..1700775 (-) 1545 WP_076026610.1 ABC-F family ATP-binding cassette domain-containing protein -
  LB080_RS09020 (LB080_09025) - 1700790..1701167 (-) 378 WP_003621149.1 hypothetical protein -
  LB080_RS09025 (LB080_09030) - 1701286..1702425 (-) 1140 WP_003624372.1 LCP family protein -
  LB080_RS09030 (LB080_09035) - 1702765..1704063 (+) 1299 WP_076026611.1 RNA-guided endonuclease InsQ/TnpB family protein -
  LB080_RS09035 (LB080_09040) pepF 1704386..1706188 (+) 1803 WP_076026612.1 oligoendopeptidase F Regulator
  LB080_RS09040 (LB080_09045) - 1706258..1706890 (-) 633 Protein_1714 alpha-hydroxy-acid oxidizing protein -
  LB080_RS10230 - 1707017..1707190 (+) 174 WP_014565366.1 hypothetical protein -
  LB080_RS09045 (LB080_09050) - 1707259..1707702 (-) 444 WP_076026614.1 zinc ribbon domain-containing protein -
  LB080_RS09050 (LB080_09055) - 1707839..1708636 (-) 798 WP_003621140.1 metal ABC transporter permease -
  LB080_RS09055 (LB080_09060) - 1708636..1709289 (-) 654 WP_014565368.1 metal ABC transporter ATP-binding protein -
  LB080_RS09060 (LB080_09065) - 1709315..1710115 (-) 801 WP_003621136.1 HAD family hydrolase -
  LB080_RS09065 (LB080_09070) - 1710381..1712351 (-) 1971 WP_011544297.1 fructose-specific PTS transporter subunit EIIC -
  LB080_RS09070 (LB080_09075) pfkB 1712400..1713314 (-) 915 WP_076026615.1 1-phosphofructokinase -
  LB080_RS09075 (LB080_09080) - 1713314..1714063 (-) 750 WP_011544299.1 DeoR/GlpR family DNA-binding transcription regulator -
  LB080_RS09085 (LB080_09090) - 1714225..1714974 (-) 750 WP_003613284.1 aspartate/glutamate racemase family protein -
  LB080_RS09090 (LB080_09095) - 1714988..1716538 (-) 1551 WP_003621127.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase -
  LB080_RS09095 (LB080_09100) - 1716575..1717783 (-) 1209 WP_076026616.1 sensor histidine kinase -
  LB080_RS09100 (LB080_09105) - 1717773..1718459 (-) 687 WP_076026617.1 response regulator transcription factor -
  LB080_RS09105 (LB080_09110) - 1718588..1720432 (-) 1845 WP_076026618.1 ABC transporter ATP-binding protein -
  LB080_RS09110 (LB080_09115) - 1720443..1722170 (-) 1728 WP_076026619.1 ABC transporter ATP-binding protein -
  LB080_RS09115 (LB080_09120) - 1722308..1723078 (-) 771 WP_076026620.1 DUF1129 domain-containing protein -
  LB080_RS09120 (LB080_09125) ychF 1723093..1724193 (-) 1101 WP_076026621.1 redox-regulated ATPase YchF -
  LB080_RS09125 (LB080_09130) - 1724270..1724533 (-) 264 WP_003621115.1 DUF951 domain-containing protein -
  LB080_RS09130 (LB080_09135) - 1724526..1725419 (-) 894 WP_003624700.1 ParB/RepB/Spo0J family partition protein -
  LB080_RS09135 (LB080_09140) - 1725397..1726176 (-) 780 WP_076026622.1 ParA family protein -
  LB080_RS09140 (LB080_09145) noc 1726178..1727002 (-) 825 WP_002879525.1 nucleoid occlusion protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 68228.03 Da        Isoelectric Point: 4.4766

>NTDB_id=213313 LB080_RS09035 WP_076026612.1 1704386..1706188(+) (pepF) [Lactobacillus delbrueckii subsp. bulgaricus strain DSM 20080]
MEIPYRSEVPKEQTWDLTRVFKTEADWEAAFKAVKQEVKALPALEDGFTESAAVLYDRLTQIFAVDRRLSKIYVYASMAS
DVDTSNQKKLALNSRGQSLAAEYQAAVAFIQPAVLALGKEGLDAFFKEEPRLENYRHYLEQIVKQEEHVLPAEEEKLVSA
AGDALSASANTFNVLTNSDLQFPYIEDEDGEAVELTEANYDILIQSQNREVREDAFDALYAGYGQFASTFASTLAGNVKA
HNFDAQTHHYQDALAAALSENNIPVDVYNQLLTSVHKHLDLLHRYVNLREEILDLKGDLQMWDMYVPITGKPSLSYTFAE
AKAQAREALQVLGEDYVKHVDYLFNNRCIDHVANMHKQSGAYSGGAYDTDAYVLLNWQGDLDSLYTLVHETGHSVHSMYT
RENQPYVYGDYPIFVAEIASTTNENLLTNYFLDRVTDPKTRAFLLNYYLSSFKGTVYRQTQFAEFEKFIHESDQAGEALT
ADYLCGFYDRLNQQYYGPAISLGSDIDLEWARIPHFYYNFYVYQYATGFAAATALANKITYGSQEDKEKYLDFLKSGSSD
YPINIMQKAGVDMTKSDYLEDAFKVFAERLDEFTDLIKKL

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=213313 LB080_RS09035 WP_076026612.1 1704386..1706188(+) (pepF) [Lactobacillus delbrueckii subsp. bulgaricus strain DSM 20080]
ATGGAAATCCCTTATCGCAGTGAGGTTCCCAAAGAACAGACCTGGGACTTGACCCGGGTCTTCAAGACTGAGGCGGACTG
GGAGGCCGCCTTTAAAGCTGTCAAGCAGGAAGTCAAGGCCCTGCCGGCCTTGGAAGACGGCTTTACGGAGAGCGCGGCCG
TCCTTTATGACCGCTTGACCCAGATTTTTGCCGTTGACCGCCGCCTGTCCAAGATCTACGTCTATGCCAGCATGGCCAGC
GACGTCGACACCAGCAACCAGAAGAAGCTGGCCCTCAATTCCCGCGGCCAGAGCCTGGCCGCTGAATACCAGGCGGCTGT
TGCCTTCATTCAGCCGGCTGTTTTAGCCTTGGGGAAAGAGGGCCTGGACGCCTTTTTCAAGGAAGAGCCAAGACTGGAAA
ACTACCGGCACTATTTGGAACAGATCGTCAAGCAGGAAGAGCACGTTTTGCCAGCTGAAGAGGAGAAGCTGGTATCGGCG
GCCGGGGATGCCCTGTCAGCTTCGGCCAACACCTTCAACGTCTTGACCAACTCCGATTTGCAATTCCCCTACATTGAAGA
TGAAGACGGGGAAGCAGTGGAACTGACGGAAGCCAACTACGACATCTTGATCCAGTCCCAGAACCGGGAAGTCAGAGAGG
ACGCCTTTGACGCCCTTTACGCTGGCTACGGCCAGTTCGCGTCAACTTTTGCCTCAACCTTGGCCGGCAATGTCAAGGCC
CACAACTTTGATGCCCAGACCCACCACTACCAGGACGCCTTAGCCGCGGCTCTGTCAGAAAACAACATCCCTGTCGACGT
ATACAACCAGCTTTTGACTAGCGTCCACAAGCACCTGGACCTCCTCCACCGCTATGTCAACTTGCGCGAAGAGATCCTGG
ACCTGAAGGGCGACCTGCAAATGTGGGACATGTACGTGCCGATCACGGGCAAGCCAAGCCTCAGCTACACTTTCGCTGAA
GCCAAGGCCCAGGCCAGAGAGGCCCTGCAGGTTTTGGGCGAGGACTATGTCAAACACGTCGACTACCTCTTCAATAACCG
CTGCATCGACCACGTGGCTAACATGCACAAGCAAAGCGGGGCCTACTCCGGCGGGGCTTATGACACCGACGCCTATGTGC
TCTTGAACTGGCAGGGGGACCTGGATTCCCTCTACACCCTGGTCCACGAGACCGGCCACTCAGTCCACAGCATGTACACC
CGGGAAAACCAGCCATACGTGTACGGGGACTATCCGATCTTTGTCGCGGAAATTGCCTCAACGACCAATGAAAACCTGCT
GACCAACTACTTCCTGGACCGGGTGACGGATCCAAAGACCCGGGCCTTCCTGCTCAACTACTACTTGAGCTCCTTTAAGG
GAACGGTCTACCGGCAGACCCAGTTCGCGGAATTCGAGAAGTTCATTCATGAAAGCGACCAGGCGGGGGAAGCCTTGACG
GCTGACTACCTGTGCGGCTTCTACGACCGGCTCAACCAGCAGTACTACGGCCCAGCGATCAGCCTGGGCAGCGACATCGA
CCTGGAATGGGCCCGGATCCCCCACTTCTATTACAACTTCTACGTCTACCAGTACGCGACCGGCTTTGCCGCGGCGACTG
CCCTGGCTAACAAGATTACTTACGGCAGCCAGGAAGACAAGGAGAAGTACCTGGACTTCCTTAAGTCCGGCTCCAGCGAC
TACCCGATCAACATCATGCAGAAGGCCGGCGTCGACATGACCAAGTCCGACTACCTGGAAGATGCCTTCAAGGTCTTTGC
GGAAAGACTGGACGAATTTACTGACTTAATCAAAAAATTGTAG

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(203-584)

Oligopeptidase F (Peptidase_M3_N)

(115-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.832

99

0.493

Multiple sequence alignment