Detailed information NTG0021299

Bioinformatically predicted

Overview

• Name: ccrA
• Type: Machinery gene
• Locus tag: SAS_RS00175
• Genome accession: NC_002953
• Coordinates: 44478..45827 (-)
• Length: 449 a.a.
• NCBI ID: WP_000806248.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus MSSA476
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	42831..45827	44478..45827	within	0

Gene organization within MGE regions

Location: 42831..45827

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAS_RS00170 (SAS0032)	ccrB	42831..44456 (-)	1626	WP_000359817.1	cassette chromosome recombinase CcrB	Machinery gene
SAS_RS00175 (SAS0033)	ccrA	44478..45827 (-)	1350	WP_000806248.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 52370.09 Da
• Isoelectric Point: 9.8433

>NTDB_id=21299 SAS_RS00175 WP_000806248.1 44478..45827(-) (ccrA) [Staphylococcus aureus subsp. aureus MSSA476]
MKQAIGYLRQSTTKQQSLAAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQTYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVKNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKSPTVKAVFNYYLQGYGYKKIAQYLEADDNFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEEAQVTRTQKQVKCKPSENQLKQKIKCPYCHSTLTNMTVRKPDHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDIEIKTTLNHEQLIEKLAQGKIDAETFKEQTHSLHQQSKPISSISAYQIRKAFQ
NIIQQRFTLNMLYPYIDEINISKNKSLAGIYFKNEPLNIVKQTMKLSIV

Nucleotide

• Length: 1350 bp

>NTDB_id=21299 SAS_RS00175 WP_000806248.1 44478..45827(-) (ccrA) [Staphylococcus aureus subsp. aureus MSSA476]
ATGAAACAAGCAATAGGTTACTTACGACAGAGCACTACAAAGCAACAATCCTTAGCAGCACAAAAACAAACCATCAAGGC
ATTAGCCGAAAAACATAATATTCAACACATTACCTTTTATAGCGATAAACAATCAGGACGTACTGATAAGCGGAATGGTT
ATCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTATTATGTTGCTATCGTCTAAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAGCTCATGAAATTATGTCAAACGTATCATGTTCATATCTTAAGCGTTCATGATGGCTACTTCGA
CATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAACTAGAATCTGATAATATAGGCGAAC
AAGTCAAAAATGGAATCAAAGAAAAAGCGAGACAAGGTAAACTAATTACAACACATGCGCCCTTTGGGTATCACTATCAT
AATGGTACTTTCACGATAGACACAGTAAAGTCACCAACAGTAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATGATAACTTCATTAATCGCAAGCCTTATCAAGTGCGTAATATTATCCTCA
ATCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TACGAAGAAGCTCAAGTTACCCGAACTCAGAAACAAGTAAAATGTAAGCCGTCAGAAAATCAACTCAAACAAAAAATCAA
ATGTCCCTATTGTCATTCGACACTCACAAACATGACTGTCCGAAAACCAGATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACAAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAACCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TATAGAAATTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGAAACGTTCA
AAGAACAAACGCACTCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCGAAAAGCTTTCCAA
AACATCATTCAACAACGTTTCACGCTAAACATGTTGTACCCCTATATTGATGAAATTAATATTTCTAAAAATAAAAGCCT
CGCTGGCATCTATTTCAAAAACGAACCACTGAATATTGTAAAGCAGACTATGAAATTATCAATTGTATAA

Domains

Predicted by InterproScan.

• Recombinase (Recombinase) (170-249)

• Recombinase zinc beta ribbon domain (Zn_ribbon_recom) (262-322)

• Resolvase, N terminal domain (Resolvase) (4-147)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrA	Staphylococcus aureus COL	94.655	100	0.947
ccrA	Staphylococcus aureus N315	74.61	100	0.746