Detailed information NTG0021295

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SAR_RS14220
• Genome accession: NC_002952
• Coordinates: 2796659..2797324 (-)
• Length: 221 a.a.
• NCBI ID: WP_000697879.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus MRSA252
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	2797873..2798820	2796659..2797324	flank	549

Gene organization within MGE regions

Location: 2796659..2798820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAR_RS14220 (SAR2703)	braR	2796659..2797324 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SAR_RS14225 (SAR2704)	-	2797350..2797550 (-)	201	WP_000604727.1	hypothetical protein	-
SAR_RS14235 (SAR2705)	-	2797873..2798820 (+)	948	WP_000121211.1	IS30-like element ISSau1 family transposase	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25388.46 Da
• Isoelectric Point: 4.7961

>NTDB_id=21295 SAR_RS14220 WP_000697879.1 2796659..2797324(-) (braR) [Staphylococcus aureus subsp. aureus MRSA252]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQSIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide

• Length: 666 bp

>NTDB_id=21295 SAR_RS14220 WP_000697879.1 2796659..2797324(-) (braR) [Staphylococcus aureus subsp. aureus MRSA252]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAGCATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-220)

• Response regulator receiver domain (Response_reg) (3-111)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	99.548	100	0.995