Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   LPB137_RS04680 Genome accession   NZ_CP019070
Coordinates   952995..954839 (-) Length   614 a.a.
NCBI ID   WP_076085044.1    Uniprot ID   A0A1P8KKV6
Organism   Poseidonibacter parvus strain LPB0137     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 947995..959839
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB137_RS04665 (LPB137_04665) - 948222..948983 (+) 762 WP_076085034.1 competence/damage-inducible protein A -
  LPB137_RS04670 (LPB137_04670) - 949087..952050 (+) 2964 WP_076085039.1 nitrate- and nitrite sensing domain-containing protein -
  LPB137_RS04675 (LPB137_04675) - 952070..952555 (-) 486 WP_076085041.1 tetratricopeptide repeat protein -
  LPB137_RS04680 (LPB137_04680) uvrC 952995..954839 (-) 1845 WP_076085044.1 excinuclease ABC subunit UvrC Machinery gene
  LPB137_RS04685 (LPB137_04685) - 954931..955641 (+) 711 WP_076085047.1 SOS response-associated peptidase -
  LPB137_RS04690 (LPB137_04690) - 955638..956396 (-) 759 WP_076085050.1 phosphotransferase -
  LPB137_RS04695 (LPB137_04695) - 956405..956884 (-) 480 WP_076089214.1 glutathione peroxidase -
  LPB137_RS04705 (LPB137_04705) - 957228..957698 (-) 471 WP_076085053.1 hypothetical protein -
  LPB137_RS04710 (LPB137_04710) - 957760..958158 (-) 399 WP_076085056.1 winged helix-turn-helix transcriptional regulator -
  LPB137_RS04715 (LPB137_04715) - 958314..958976 (+) 663 WP_197682251.1 NAD(P)H-dependent oxidoreductase -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 72165.31 Da        Isoelectric Point: 8.9581

>NTDB_id=212933 LPB137_RS04680 WP_076085044.1 952995..954839(-) (uvrC) [Poseidonibacter parvus strain LPB0137]
MQLEEKLKQLPNDAGVYQYFDKDGRLLYIGKAKVLKNRVKSYFKFTPKLLPSDRLGPRIYKMISEAFSIEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYIDYSELYPRLEITRKVYKNKNIKYFGPYSTGSRDMLDSIYEIVPLVQKKSC
IKGKEACLFHQIKRCHAPCEGKITTGEYYKIVEEAIDYIYNKSKLIVKLQEKMLEYSEDFRFEEAMKLRDRIKTIEKSQI
KSGMDLATNENLDVFAIKASKQKAVIVRMFIRDGKLTSSSYDFIKVNFLEDETNIDLDEAYKRAIVNYYDNEIPLLPKEI
LTAIDIEEKNDLEEFLYNRFEKRIKLVNPKKDKKKDLIQIALNNCDELLRIDSSRNQSTIYEELQKLFNLQILPHRVETY
DNSHMMGQATVGAMVVWNEELNAFDKKDFRHYNLESKDEYSQMREILMRRVDSFEKNPAPDLWILDGGSALLKLAYDIIN
STGVNLDIIAIAKEKVDAKAHRAKGAAKDIVHYKDEKGEYRSLKLETSDQRLQFVQRQRDEAHRFVISFHKKQKRKEDKQ
ISLLQIKGIGEAKVKKLLLYFGEFEKIRNASIEELKEVLNEKDAIVISTYFKEE

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=212933 LPB137_RS04680 WP_076085044.1 952995..954839(-) (uvrC) [Poseidonibacter parvus strain LPB0137]
ATGCAATTAGAAGAAAAACTAAAACAATTACCAAATGATGCTGGCGTTTATCAATACTTCGATAAAGATGGAAGACTACT
ATATATAGGAAAAGCAAAAGTACTAAAAAATAGAGTTAAATCTTACTTTAAATTTACACCAAAACTACTTCCTTCTGATA
GATTAGGTCCTAGAATTTATAAAATGATAAGTGAAGCTTTTAGTATTGAGTGGATTGTAGTACCAAATGAACATGATGCA
TTAATTTTAGAAAATTCTTTAATTAAACAACTAAAACCAAAGTACAATATTTTACTTCGTGATGATAAAACCTATCCATA
CATTTACATAGATTACTCAGAACTTTACCCTAGACTTGAAATTACAAGAAAAGTTTATAAAAATAAAAATATTAAATATT
TTGGACCCTATTCTACTGGCTCTCGTGATATGCTTGATAGTATTTATGAAATAGTTCCTTTAGTTCAAAAAAAATCATGT
ATAAAAGGAAAAGAAGCATGTTTATTTCATCAGATTAAAAGGTGTCATGCACCTTGTGAAGGTAAAATAACAACAGGTGA
GTATTATAAAATAGTTGAAGAAGCTATTGATTATATTTATAATAAATCAAAATTAATTGTAAAACTTCAAGAAAAAATGC
TTGAATACTCTGAAGATTTTAGATTTGAAGAAGCAATGAAACTTCGAGATAGAATTAAAACAATTGAAAAATCACAAATA
AAATCAGGTATGGACCTAGCAACAAATGAAAATCTTGATGTATTTGCAATAAAAGCATCAAAACAAAAAGCTGTAATAGT
AAGAATGTTTATAAGAGATGGAAAACTAACCTCTTCTTCTTATGATTTTATAAAAGTAAATTTTTTAGAAGATGAAACTA
ATATTGATTTAGATGAAGCATATAAAAGAGCTATTGTAAATTATTATGACAATGAAATTCCATTATTACCAAAAGAGATT
TTAACAGCAATTGATATTGAAGAAAAAAATGACTTAGAAGAGTTTTTATACAATAGATTTGAAAAAAGAATAAAACTAGT
TAATCCTAAGAAAGATAAGAAAAAAGATTTAATTCAAATTGCACTTAACAATTGTGATGAACTCCTTAGAATTGATTCCT
CTAGAAATCAAAGTACTATATATGAAGAACTTCAGAAGCTATTTAATCTTCAAATACTTCCACATAGAGTTGAAACCTAT
GATAACTCACATATGATGGGACAAGCAACTGTTGGAGCTATGGTTGTTTGGAATGAAGAACTAAATGCCTTTGATAAAAA
AGATTTCAGACACTATAATCTTGAATCAAAAGATGAATATTCTCAAATGAGAGAAATATTAATGAGAAGGGTTGATAGTT
TTGAGAAAAATCCAGCACCTGATCTTTGGATATTAGATGGTGGGTCAGCACTGCTAAAATTAGCCTATGATATTATTAAT
TCAACTGGTGTGAATTTAGATATTATTGCAATTGCAAAAGAAAAAGTTGATGCAAAAGCTCATAGAGCAAAAGGTGCTGC
AAAAGATATTGTTCACTATAAAGATGAAAAAGGTGAATACAGGTCTTTAAAACTAGAAACAAGTGATCAAAGATTACAAT
TTGTTCAAAGACAAAGAGATGAAGCTCATAGATTTGTAATCAGCTTTCATAAAAAACAAAAAAGAAAAGAAGATAAGCAA
ATTTCATTACTTCAAATAAAAGGAATAGGAGAAGCAAAGGTAAAAAAACTTCTTTTATATTTTGGAGAATTTGAGAAAAT
TAGAAATGCTTCAATAGAAGAGTTAAAAGAAGTTCTAAACGAAAAAGATGCGATTGTAATTTCAACTTATTTTAAAGAAG
AATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-547)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1P8KKV6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.831

98.046

0.498

Multiple sequence alignment