Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxS   Type   Regulator
Locus tag   A5960_RS00335 Genome accession   NZ_CP024289
Coordinates   60123..60638 (+) Length   171 a.a.
NCBI ID   WP_001130210.1    Uniprot ID   B6I678
Organism   Escherichia coli O178:H19 strain 2012C-4431     
Function   induction of competence (predicted from homology)   
Competence regulation

Genomic Context

Location: 55123..65638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A5960_RS00285 csrA 55435..55620 (+) 186 WP_000906486.1 carbon storage regulator CsrA -
  A5960_RS00320 yqaB 57353..57919 (+) 567 WP_000273309.1 fructose-1-phosphate/6-phosphogluconate phosphatase -
  A5960_RS00325 yqaA 57916..58344 (+) 429 WP_001287457.1 YqaA family protein -
  A5960_RS00330 gshA 58417..59973 (+) 1557 WP_000611802.1 glutamate--cysteine ligase -
  A5960_RS00335 luxS 60123..60638 (+) 516 WP_001130210.1 S-ribosylhomocysteine lyase Regulator
  A5960_RS00340 emrB 60702..62240 (-) 1539 WP_001295176.1 multidrug efflux MFS transporter permease subunit EmrB -
  A5960_RS00345 emrA 62257..63429 (-) 1173 WP_001295175.1 multidrug efflux MFS transporter periplasmic adaptor subunit EmrA -
  A5960_RS00350 emrR 63556..64086 (-) 531 WP_000378442.1 multidrug efflux transporter EmrAB transcriptional repressor EmrR -
  A5960_RS00355 ygaH 64177..64512 (-) 336 WP_000119763.1 L-valine transporter subunit YgaH -
  A5960_RS00360 ygaZ 64502..65239 (-) 738 WP_000445658.1 L-valine exporter subunit YgaZ -

Sequence

Protein


Download         Length: 171 a.a.        Molecular weight: 19417.13 Da        Isoelectric Point: 4.7556

>NTDB_id=212648 A5960_RS00335 WP_001130210.1 60123..60638(+) (luxS) [Escherichia coli O178:H19 strain 2012C-4431]
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
LPEEKLQELHI

Nucleotide


Download         Length: 516 bp        

>NTDB_id=212648 A5960_RS00335 WP_001130210.1 60123..60638(+) (luxS) [Escherichia coli O178:H19 strain 2012C-4431]
ATGCCGTTGTTAGATAGCTTCACAGTCGATCATACCCGGATGGAAGCGCCTGCAGTTCGGGTGGCGAAAACAATGAACAC
CCCGCATGGCGACGCAATCACCGTGTTCGATCTGCGCTTCTGCGTGCCGAACAAAGAAGTGATGCCAGAAAGAGGGATCC
ATACCCTGGAGCACCTGTTTGCTGGTTTTATGCGTAACCATCTTAACGGTAATGGTGTAGAGATTATCGATATCTCGCCA
ATGGGCTGCCGCACCGGTTTTTATATGAGTCTGATTGGTACGCCAGATGAGCAGCGTGTTGCTGATGCCTGGAAAGCGGC
AATGGAAGACGTGCTGAAAGTGCAGGATCAGAATCAGATCCCGGAACTGAACGTCTACCAGTGTGGCACTTACCAGATGC
ACTCGTTGCAGGAAGCGCAGGATATTGCGCGTAGCATTCTGGAACGTGACGTACGCATCAACAGCAACGAAGAACTGGCG
CTGCCGGAAGAGAAGTTGCAGGAACTGCACATTTAG

Domains

Predicted by InterProScan.

S-Ribosylhomocysteinase (LuxS) (LuxS)

(4-152)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B6I678

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxS Vibrio cholerae strain A1552

73.684

100

0.737