Detailed information NTG0021250

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SACOL_RS13855
• Genome accession: NC_002951
• Coordinates: 2705765..2706652 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus subsp. aureus COL
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2700765..2711652

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SACOL_RS13820 (SA2640)	-	2700784..2700876 (+)	93	WP_010956583.1	hypothetical protein	-
SACOL_RS13825 (SA2641)	-	2700984..2701481 (-)	498	WP_001065268.1	glutathione peroxidase	-
SACOL_RS13830	-	2701491..2701751 (-)	261	WP_001789910.1	hypothetical protein	-
SACOL_RS13835	-	2702133..2702246 (-)	114	WP_011447078.1	hypothetical protein	-
SACOL_RS13845 (SA2643)	-	2702905..2704905 (-)	2001	WP_000776751.1	ABC transporter permease	-
SACOL_RS13850 (SA2644)	-	2704902..2705657 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
SACOL_RS13855 (SA2645)	braS	2705765..2706652 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SACOL_RS13860 (SA2646)	braR	2706663..2707328 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SACOL_RS13865 (SA2647)	-	2707354..2707554 (-)	201	WP_000604728.1	hypothetical protein	-
SACOL_RS13875 (SA2648)	-	2707752..2709176 (+)	1425	WP_000953744.1	alkaline phosphatase	-
SACOL_RS15250	-	2709246..2709356 (+)	111	WP_001791296.1	hypothetical protein	-
SACOL_RS13880 (SA2650)	-	2709459..2709914 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SACOL_RS13885 (SA2651)	-	2710159..2710920 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=21250 SACOL_RS13855 WP_000143419.1 2705765..2706652(-) (braS) [Staphylococcus aureus subsp. aureus COL]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=21250 SACOL_RS13855 WP_000143419.1 2705765..2706652(-) (braS) [Staphylococcus aureus subsp. aureus COL]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997