Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   COG37_RS03350 Genome accession   NZ_CP024257
Coordinates   680753..681385 (-) Length   210 a.a.
NCBI ID   WP_001735800.1    Uniprot ID   -
Organism   Escherichia coli O25:H16 strain F5505-C1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 675753..686385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  COG37_RS03325 yhfG 675885..676052 (+) 168 WP_000736860.1 YhfG family protein -
  COG37_RS03330 fic 676042..676644 (+) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  COG37_RS03335 pabA 676676..677239 (+) 564 WP_000601847.1 aminodeoxychorismate synthase component 2 -
  COG37_RS03340 argD 677325..678545 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  COG37_RS03345 yhfK 678612..680702 (-) 2091 WP_001295162.1 YccS/YhfK family putative transporter -
  COG37_RS03350 crp 680753..681385 (-) 633 WP_001735800.1 cAMP-activated global transcriptional regulator CRP Regulator
  COG37_RS03360 yhfA 681687..682091 (+) 405 WP_001148908.1 OsmC family protein -
  COG37_RS03365 prkB 682146..683015 (-) 870 WP_001274680.1 phosphoribulokinase -
  COG37_RS03370 yheU 683069..683286 (-) 218 Protein_623 YheU family protein -
  COG37_RS03375 yheT 683280..684302 (-) 1023 WP_000057356.1 hydrolase -
  COG37_RS03380 yheS 684302..686215 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23649.44 Da        Isoelectric Point: 8.2778

>NTDB_id=212096 COG37_RS03350 WP_001735800.1 680753..681385(-) (crp) [Escherichia coli O25:H16 strain F5505-C1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGHIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=212096 COG37_RS03350 WP_001735800.1 680753..681385(-) (crp) [Escherichia coli O25:H16 strain F5505-C1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCAGACGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCATATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTTGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.238

100

0.952
  crp Haemophilus influenzae Rd KW20

77.451

97.143

0.752
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment