Detailed information NTG0211727

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: BVD85_RS07935
• Genome accession: NZ_CP018908
• Coordinates: 1570733..1571782 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain SS2-1
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1565733..1576782

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BVD85_RS07915 (BVD85_07915)	nadE	1566139..1566963 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
BVD85_RS07920 (BVD85_07920)	-	1568259..1568786 (-)	528	WP_012027591.1	VanZ family protein	-
BVD85_RS07925 (BVD85_07925)	rlmN	1568783..1569895 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
BVD85_RS07930 (BVD85_07930)	-	1569904..1570545 (-)	642	WP_012027595.1	YutD family protein	-
BVD85_RS07935 (BVD85_07935)	sepM	1570733..1571782 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
BVD85_RS07940 (BVD85_07940)	coaD	1571769..1572257 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
BVD85_RS07945 (BVD85_07945)	rsmD	1572247..1572786 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
BVD85_RS07950 (BVD85_07950)	-	1573094..1573816 (-)	723	WP_012027598.1	lipoprotein	-
BVD85_RS07955 (BVD85_07955)	-	1573873..1574259 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
BVD85_RS07960 (BVD85_07960)	-	1574259..1574477 (-)	219	WP_004194736.1	YqgQ family protein	-
BVD85_RS07965 (BVD85_07965)	-	1574785..1575387 (-)	603	WP_012027601.1	response regulator transcription factor	-
BVD85_RS07970 (BVD85_07970)	-	1575384..1576478 (-)	1095	WP_199764253.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=211727 BVD85_RS07935 WP_012775295.1 1570733..1571782(-) (sepM) [Streptococcus suis strain SS2-1]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=211727 BVD85_RS07935 WP_012775295.1 1570733..1571782(-) (sepM) [Streptococcus suis strain SS2-1]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605