Detailed information NTG0210838

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: BUM80_RS07225
• Genome accession: NZ_CP018838
• Coordinates: 1332258..1333295 (-)
• Length: 345 a.a.
• NCBI ID: WP_001813016.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 11A
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1327258..1338295

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS07200 (BUM80_07410)	-	1327997..1329328 (-)	1332	WP_000390042.1	hemolysin family protein	-
BUM80_RS07205 (BUM80_07415)	endA	1329619..1330443 (-)	825	WP_001036791.1	DNA-entry nuclease EndA	Machinery gene
BUM80_RS07210 (BUM80_07420)	-	1330482..1330670 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
BUM80_RS07215 (BUM80_07425)	murA	1330663..1331946 (-)	1284	WP_000358032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
BUM80_RS07220 (BUM80_07430)	-	1331970..1332200 (-)	231	WP_000250390.1	DUF1146 family protein	-
BUM80_RS07225 (BUM80_07435)	sepM	1332258..1333295 (-)	1038	WP_001813016.1	SepM family pheromone-processing serine protease	Regulator
BUM80_RS07230 (BUM80_07440)	coaD	1333279..1333767 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
BUM80_RS07235 (BUM80_07445)	rsmD	1333757..1334296 (-)	540	WP_000706963.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
BUM80_RS07240 (BUM80_07450)	asnA	1334361..1335353 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
BUM80_RS07250 (BUM80_07460)	-	1335465..1336148 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
BUM80_RS07255 (BUM80_07465)	-	1336204..1336944 (-)	741	WP_000152679.1	RNA methyltransferase	-
BUM80_RS07260 (BUM80_07470)	-	1336978..1337256 (+)	279	WP_001174614.1	acylphosphatase	-
BUM80_RS07265 (BUM80_07475)	yidC	1337334..1338260 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37609.64 Da
• Isoelectric Point: 4.9590

>NTDB_id=210838 BUM80_RS07225 WP_001813016.1 1332258..1333295(-) (sepM) [Streptococcus pneumoniae strain 11A]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKEIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIDLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=210838 BUM80_RS07225 WP_001813016.1 1332258..1333295(-) (sepM) [Streptococcus pneumoniae strain 11A]
ATGAAAAAAAAGATTAGATGGCCTTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGAAATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGACTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588