Detailed information NTG0210828

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: BUM80_RS06775
• Genome accession: NZ_CP018838
• Coordinates: 1257844..1258911 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain 11A
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1252844..1263911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS06750 (BUM80_06935)	treR	1253031..1253741 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
BUM80_RS06755 (BUM80_06940)	-	1253774..1254577 (-)	804	WP_000157672.1	ABC transporter ATP-binding protein	-
BUM80_RS06760	-	1254590..1255467 (-)	878	Protein_1280	ABC transporter permease	-
BUM80_RS06765 (BUM80_06955)	-	1255479..1256288 (-)	810	Protein_1281	ABC transporter substrate-binding protein	-
BUM80_RS06770 (BUM80_06960)	amiF	1256907..1257833 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
BUM80_RS06775 (BUM80_06965)	amiE	1257844..1258911 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
BUM80_RS06780 (BUM80_06970)	amiD	1258920..1259846 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
BUM80_RS06785 (BUM80_06975)	amiC	1259846..1261342 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
BUM80_RS06790 (BUM80_06980)	amiA3	1261409..1263388 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=210828 BUM80_RS06775 WP_000159554.1 1257844..1258911(-) (amiE) [Streptococcus pneumoniae strain 11A]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=210828 BUM80_RS06775 WP_000159554.1 1257844..1258911(-) (amiE) [Streptococcus pneumoniae strain 11A]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541