Detailed information NTG0210810

Bioinformatically predicted

Overview

• Name: vicX
• Type: Regulator
• Locus tag: BUM80_RS03305
• Genome accession: NZ_CP018838
• Coordinates: 637338..638147 (-)
• Length: 269 a.a.
• NCBI ID: WP_001289493.1
• Uniprot ID: Q9RCS5
• Organism: Streptococcus pneumoniae strain 11A
• Function: require for competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	636019..637275	637338..638147	flank	63

Gene organization within MGE regions

Location: 636019..638147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUM80_RS03300 (BUM80_03405)	-	636019..637275 (+)	1257	WP_000530078.1	ISL3 family transposase	-
BUM80_RS03305 (BUM80_03410)	vicX	637338..638147 (-)	810	WP_001289493.1	MBL fold metallo-hydrolase	Regulator

Sequence

Protein

• Length: 269 a.a.
• Molecular weight: 29916.89 Da
• Isoelectric Point: 6.1743

>NTDB_id=210810 BUM80_RS03305 WP_001289493.1 637338..638147(-) (vicX) [Streptococcus pneumoniae strain 11A]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide

• Length: 810 bp

>NTDB_id=210810 BUM80_RS03305 WP_001289493.1 637338..638147(-) (vicX) [Streptococcus pneumoniae strain 11A]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTGGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGCAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACTTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGACAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (15-223)

3D structure

• AlphaFold DB: Q9RCS5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicX	Streptococcus mutans UA159	77.323	100	0.773