Detailed information NTG0210116

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: BSG37_RS14280
• Genome accession: NZ_CP018768
• Coordinates: 2733087..2733974 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain UCI 28 isolate ST5
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2728087..2738974

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSG37_RS14245 (BSG37_14265)	-	2728106..2728198 (+)	93	WP_010956583.1	hypothetical protein	-
BSG37_RS14250 (BSG37_14270)	-	2728306..2728803 (-)	498	WP_001065268.1	glutathione peroxidase	-
BSG37_RS14255 (BSG37_14275)	-	2728813..2729073 (-)	261	WP_001791974.1	hypothetical protein	-
BSG37_RS14265 (BSG37_14285)	-	2729455..2729568 (-)	114	Protein_2647	hypothetical protein	-
BSG37_RS14270 (BSG37_14290)	-	2730227..2732227 (-)	2001	WP_000776750.1	ABC transporter permease	-
BSG37_RS14275 (BSG37_14295)	-	2732224..2732979 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
BSG37_RS14280 (BSG37_14300)	braS	2733087..2733974 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
BSG37_RS14285 (BSG37_14305)	braR	2733985..2734650 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
BSG37_RS14290 (BSG37_14310)	-	2734676..2734876 (-)	201	WP_000604730.1	hypothetical protein	-
BSG37_RS14295 (BSG37_14315)	-	2735074..2736498 (+)	1425	WP_000953755.1	alkaline phosphatase	-
BSG37_RS15540 (BSG37_14320)	-	2736558..2736659 (-)	102	WP_000731976.1	SE2200 family small protein	-
BSG37_RS14305 (BSG37_14325)	-	2736781..2737236 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
BSG37_RS14310 (BSG37_14330)	-	2737481..2738242 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=210116 BSG37_RS14280 WP_000143425.1 2733087..2733974(-) (braS) [Staphylococcus aureus strain UCI 28 isolate ST5]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=210116 BSG37_RS14280 WP_000143425.1 2733087..2733974(-) (braS) [Staphylococcus aureus strain UCI 28 isolate ST5]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1