Detailed information NTG0210065

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: BSG38_RS10695
• Genome accession: NZ_CP018766
• Coordinates: 2064078..2065121 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain UCI62
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2059078..2070121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSG38_RS10665 (BSG38_10685)	-	2059499..2060755 (-)	1257	WP_001795108.1	aminopeptidase	-
BSG38_RS10670 (BSG38_10690)	-	2060758..2060958 (-)	201	WP_000180460.1	DUF1128 family protein	-
BSG38_RS10675 (BSG38_10695)	-	2061105..2061569 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
BSG38_RS10680 (BSG38_10700)	-	2061576..2061851 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
BSG38_RS10685 (BSG38_10705)	-	2062129..2063346 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
BSG38_RS10690 (BSG38_10710)	vraR	2063459..2064088 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
BSG38_RS10695 (BSG38_10715)	vraS	2064078..2065121 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
BSG38_RS10700 (BSG38_10720)	liaF	2065118..2065819 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
BSG38_RS10705 (BSG38_10725)	-	2065834..2066220 (-)	387	WP_001110179.1	hypothetical protein	-
BSG38_RS10710 (BSG38_10730)	map	2066437..2067195 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
BSG38_RS10720 (BSG38_10740)	-	2067726..2068712 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
BSG38_RS10735 (BSG38_10750)	-	2069143..2069556 (-)	414	WP_001557448.1	hypothetical protein	-
BSG38_RS10740 (BSG38_10755)	-	2069585..2069695 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=210065 BSG38_RS10695 WP_001017131.1 2064078..2065121(-) (vraS) [Staphylococcus aureus strain UCI62]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=210065 BSG38_RS10695 WP_001017131.1 2064078..2065121(-) (vraS) [Staphylococcus aureus strain UCI62]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1