Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   BSU_30400 Genome accession   NC_000964
Coordinates   3113187..3113882 (-) Length   231 a.a.
NCBI ID   NP_390918.1    Uniprot ID   O34951
Organism   Bacillus subtilis subsp. subtilis str. 168     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3108187..3118882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSU_30360 (BSU30360) yttA 3108614..3109360 (+) 747 NP_390914.2 hypothetical protein -
  BSU_30370 (BSU30370) bceB 3109397..3111337 (-) 1941 NP_390915.1 ABC transporter (permease) -
  BSU_30380 (BSU30380) bceA 3111327..3112088 (-) 762 NP_390916.1 bacitracin ABC efflux transporter (ATP-binding protein) -
  BSU_30390 (BSU30390) bceS 3112190..3113194 (-) 1005 NP_390917.1 two-component sensor histidine kinase controlling resistance to antibiotics affecting the envelope [YtsA] -
  BSU_30400 (BSU30400) braR 3113187..3113882 (-) 696 NP_390918.1 two-component response regulator controlling resistance to antibiotics affecting the envelope [YtsB] Regulator
  BSU_30410 (BSU30410) ytrF 3113979..3115289 (-) 1311 NP_390919.1 metabolite permease involved in resistance to cell wall inhibitors -
  BSU_30420 (BSU30420) ytrE 3115279..3115974 (-) 696 NP_390920.1 ABC transporter (ATP-binding protein) involved in resistance to cell wall inhibitors -
  BSU_30430 (BSU30430) ytrD 3115989..3116966 (-) 978 NP_390921.1 ABC transporter, permease component involved in resistance to cell wall inhibitors -
  BSU_30440 (BSU30440) ytrC 3116996..3117982 (-) 987 NP_390922.1 ABC transporter, permease component involved in resistance to cell wall inhibitors -
  BSU_30450 (BSU30450) ytrB 3117976..3118854 (-) 879 NP_390923.1 ABC transporter (ATP-binding protein) involved in resistance to cell wall inhibitors -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 26866.74 Da        Isoelectric Point: 5.3731

>NTDB_id=21005 BSU_30400 NP_390918.1 3113187..3113882(-) (braR) [Bacillus subtilis subsp. subtilis str. 168]
MFKLLLIEDDESLFHEIKDRLTGWSYDVYGIQDFSQVLQEFAAVNPDCVIIDVQLPKFDGFHWCRLIRSRSNVPILFLSS
RDHPADMVMSMQLGADDFIQKPFHFDVLIAKIQAMFRRVHHYNTEPSTIKTWCGAAVDAEQNLVSNDKGSVELTKNEMFI
LKQLIEQKNKIVSREELIRSLWNDERFVSDNTLTVNVNRLRKKLDALQLGAYIETKVGQGYIAKEEDKFYD

Nucleotide


Download         Length: 696 bp        

>NTDB_id=21005 BSU_30400 NP_390918.1 3113187..3113882(-) (braR) [Bacillus subtilis subsp. subtilis str. 168]
TTGTTTAAACTTTTGCTGATTGAAGATGATGAATCGCTGTTTCATGAAATCAAGGATCGTTTAACGGGATGGTCCTATGA
TGTATACGGCATTCAGGATTTCAGTCAGGTGCTGCAGGAATTTGCGGCGGTTAATCCTGATTGTGTCATTATTGATGTGC
AGCTGCCTAAATTTGACGGCTTTCATTGGTGCCGTCTGATCCGCTCCCGGTCAAATGTTCCGATTCTCTTTTTATCCTCC
CGGGATCATCCTGCTGATATGGTGATGTCCATGCAGCTCGGGGCAGATGACTTTATTCAAAAGCCATTTCATTTTGATGT
GCTGATCGCGAAAATCCAAGCGATGTTCCGGCGTGTGCACCATTATAATACGGAGCCGAGTACGATTAAAACGTGGTGCG
GCGCTGCTGTAGACGCGGAGCAGAACCTCGTCAGCAATGACAAAGGATCTGTTGAACTGACCAAAAATGAAATGTTCATT
CTAAAACAATTAATAGAGCAAAAAAACAAGATCGTCAGCCGGGAAGAGCTGATCAGAAGCTTGTGGAACGATGAGCGTTT
TGTTAGTGATAATACGCTGACCGTCAATGTCAATCGCCTGCGAAAAAAACTGGACGCCCTGCAGCTTGGTGCATATATCG
AGACAAAGGTGGGCCAGGGCTACATCGCGAAGGAAGAGGACAAGTTCTATGATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(150-222)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O34951

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

39.545

95.238

0.377

Multiple sequence alignment