Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | BSG38_RS00200 | Genome accession | NZ_CP018766 |
| Coordinates | 40887..42248 (-) | Length | 453 a.a. |
| NCBI ID | WP_001631036.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain UCI62 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 39262..98836 | 40887..42248 | within | 0 |
Gene organization within MGE regions
Location: 39262..98836
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BSG38_RS00195 (BSG38_00195) | ccrB | 39262..40890 (-) | 1629 | WP_001631035.1 | cassette chromosome recombinase CcrB | Machinery gene |
| BSG38_RS00200 (BSG38_00200) | ccrA | 40887..42248 (-) | 1362 | WP_001631036.1 | cassette chromosome recombinase CcrA | Machinery gene |
| BSG38_RS00205 (BSG38_00205) | - | 42435..43064 (-) | 630 | Protein_35 | hypothetical protein | - |
| BSG38_RS00210 (BSG38_00210) | - | 43073..43411 (+) | 339 | Protein_36 | recombinase family protein | - |
| BSG38_RS00215 (BSG38_00215) | - | 43523..43882 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| BSG38_RS00220 (BSG38_00220) | - | 44089..44415 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| BSG38_RS00225 (BSG38_00225) | - | 44745..46670 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| BSG38_RS00230 (BSG38_00230) | - | 47765..48394 (+) | 630 | WP_001053439.1 | hypothetical protein | - |
| BSG38_RS00235 (BSG38_00235) | - | 48409..48651 (+) | 243 | WP_000931963.1 | hypothetical protein | - |
| BSG38_RS00240 (BSG38_00240) | - | 49050..49901 (+) | 852 | WP_000832687.1 | IS3 family transposase | - |
| BSG38_RS00245 (BSG38_00245) | arcC | 50001..50930 (-) | 930 | WP_000036756.1 | carbamate kinase | - |
| BSG38_RS00250 (BSG38_00250) | argF | 50950..51948 (-) | 999 | WP_000793596.1 | ornithine carbamoyltransferase | - |
| BSG38_RS00255 (BSG38_00255) | - | 51986..52675 (-) | 690 | WP_000272781.1 | Crp/Fnr family transcriptional regulator | - |
| BSG38_RS00260 (BSG38_00260) | arcD | 52717..54138 (-) | 1422 | WP_000344142.1 | arginine-ornithine antiporter | - |
| BSG38_RS00265 (BSG38_00265) | arcA | 54224..55459 (-) | 1236 | WP_000249804.1 | arginine deiminase | - |
| BSG38_RS00270 (BSG38_00270) | - | 55728..56174 (-) | 447 | WP_000711815.1 | arginine repressor | - |
| BSG38_RS15795 | - | 56747..57429 (+) | 683 | Protein_49 | type I restriction enzyme endonuclease domain-containing protein | - |
| BSG38_RS00285 (BSG38_00285) | - | 57700..58131 (-) | 432 | WP_000475804.1 | universal stress protein | - |
| BSG38_RS00290 (BSG38_00290) | - | 59013..59339 (-) | 327 | WP_000916431.1 | hypothetical protein | - |
| BSG38_RS00295 (BSG38_00295) | - | 59355..60029 (+) | 675 | WP_001106065.1 | IS6 family transposase | - |
| BSG38_RS00300 (BSG38_00300) | - | 60789..61022 (-) | 234 | WP_000400093.1 | hypothetical protein | - |
| BSG38_RS15405 | - | 61268..66784 (+) | 5517 | WP_222102444.1 | E domain-containing protein | - |
| BSG38_RS00385 (BSG38_00385) | - | 66908..68524 (+) | 1617 | WP_000393941.1 | hypothetical protein | - |
| BSG38_RS00390 (BSG38_00390) | - | 68684..70195 (-) | 1512 | WP_000640645.1 | glycosyltransferase | - |
| BSG38_RS00395 (BSG38_00395) | - | 70218..71876 (-) | 1659 | WP_001621813.1 | Mur ligase family protein | - |
| BSG38_RS00400 (BSG38_00400) | - | 71870..72268 (-) | 399 | WP_001621810.1 | hypothetical protein | - |
| BSG38_RS00405 (BSG38_00405) | - | 73350..74606 (+) | 1257 | WP_000566670.1 | MrcB family domain-containing protein | - |
| BSG38_RS00410 (BSG38_00410) | - | 75021..75260 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| BSG38_RS00415 (BSG38_00415) | - | 75292..75966 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| BSG38_RS00420 (BSG38_00420) | - | 76231..76974 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| BSG38_RS00425 (BSG38_00425) | - | 77071..77499 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| BSG38_RS00430 (BSG38_00430) | mecA | 77545..79554 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| BSG38_RS00435 (BSG38_00435) | mecR1 | 79651..81408 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| BSG38_RS00440 (BSG38_00440) | mecI | 81408..81779 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| BSG38_RS15520 | psm-mec | 81864..81932 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| BSG38_RS00455 (BSG38_00455) | - | 82265..83395 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| BSG38_RS00460 (BSG38_00460) | cstB | 83509..84843 (-) | 1335 | Protein_69 | persulfide dioxygenase-sulfurtransferase CstB | - |
| BSG38_RS00465 (BSG38_00465) | - | 84876..85940 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| BSG38_RS00470 (BSG38_00470) | cstR | 86076..86336 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| BSG38_RS00475 (BSG38_00475) | - | 86336..86974 (+) | 639 | Protein_72 | sulfite exporter TauE/SafE family protein | - |
| BSG38_RS00485 (BSG38_00485) | - | 87319..87981 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| BSG38_RS15945 | - | 88373..88432 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| BSG38_RS00490 (BSG38_00490) | erm(A) | 88442..89173 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| BSG38_RS00495 (BSG38_00495) | - | 89299..90081 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| BSG38_RS00500 (BSG38_00500) | - | 90232..90609 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| BSG38_RS00505 (BSG38_00505) | - | 90616..92508 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| BSG38_RS00510 (BSG38_00510) | - | 92505..93590 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| BSG38_RS00515 (BSG38_00515) | - | 93709..94026 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| BSG38_RS00520 (BSG38_00520) | - | 94047..94553 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| BSG38_RS00525 (BSG38_00525) | - | 94571..94882 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| BSG38_RS00530 (BSG38_00530) | - | 94969..95319 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| BSG38_RS00535 (BSG38_00535) | ccrB | 95837..97465 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| BSG38_RS00540 (BSG38_00540) | ccrA | 97487..98836 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53316.45 Da Isoelectric Point: 9.8596
>NTDB_id=210030 BSG38_RS00200 WP_001631036.1 40887..42248(-) (ccrA) [Staphylococcus aureus strain UCI62]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=210030 BSG38_RS00200 WP_001631036.1 40887..42248(-) (ccrA) [Staphylococcus aureus strain UCI62]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.628 |
97.792 |
0.534 |
| ccrA | Staphylococcus aureus N315 |
50.564 |
97.792 |
0.494 |