Detailed information NTG0208619

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: CRD75_RS08850
• Genome accession: NZ_CP023769
• Coordinates: 1764892..1765659 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain HarveyGAS
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1759892..1770659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CRD75_RS08835 (CRD75_08835)	hexB	1760410..1762392 (-)	1983	WP_021340699.1	DNA mismatch repair endonuclease MutL	Machinery gene
CRD75_RS08840 (CRD75_08840)	-	1762487..1763638 (-)	1152	WP_003058754.1	site-specific integrase	-
CRD75_RS09730 (CRD75_08845)	-	1763887..1764030 (+)	144	WP_011185066.1	putative holin-like toxin	-
CRD75_RS08850 (CRD75_08850)	irvR	1764892..1765659 (-)	768	WP_003058809.1	S24 family peptidase	Regulator
CRD75_RS08855 (CRD75_08855)	-	1765813..1766019 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
CRD75_RS08860 (CRD75_08860)	-	1766053..1766226 (+)	174	Protein_1651	helix-turn-helix transcriptional regulator	-
CRD75_RS08865 (CRD75_08865)	-	1766274..1766681 (+)	408	WP_002992501.1	hypothetical protein	-
CRD75_RS09735	-	1766694..1766816 (+)	123	WP_011285272.1	hypothetical protein	-
CRD75_RS08870 (CRD75_08870)	-	1767099..1767620 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
CRD75_RS08875 (CRD75_08875)	-	1767868..1768041 (+)	174	WP_000132665.1	hypothetical protein	-
CRD75_RS08880 (CRD75_08880)	-	1768259..1768432 (+)	174	WP_000074663.1	hypothetical protein	-
CRD75_RS08885 (CRD75_08885)	-	1768594..1769025 (+)	432	WP_136302445.1	hypothetical protein	-
CRD75_RS08890 (CRD75_08890)	-	1769127..1769459 (+)	333	WP_011285276.1	hypothetical protein	-
CRD75_RS08895 (CRD75_08895)	-	1769459..1769650 (+)	192	WP_021340709.1	hypothetical protein	-
CRD75_RS08900 (CRD75_08900)	-	1769662..1769991 (+)	330	WP_003058810.1	hypothetical protein	-
CRD75_RS08905 (CRD75_08905)	-	1769994..1770266 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=208619 CRD75_RS08850 WP_003058809.1 1764892..1765659(-) (irvR) [Streptococcus pyogenes strain HarveyGAS]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=208619 CRD75_RS08850 WP_003058809.1 1764892..1765659(-) (irvR) [Streptococcus pyogenes strain HarveyGAS]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4