Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   CRD75_RS03070 Genome accession   NZ_CP023769
Coordinates   593589..597221 (+) Length   1210 a.a.
NCBI ID   WP_023079718.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain HarveyGAS     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 588589..602221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CRD75_RS03060 (CRD75_03060) - 589309..590226 (-) 918 WP_011284662.1 neutral zinc metallopeptidase -
  CRD75_RS03065 (CRD75_03065) rexB 590377..593592 (+) 3216 WP_011284663.1 ATP-dependent nuclease subunit B Machinery gene
  CRD75_RS03070 (CRD75_03070) rexA 593589..597221 (+) 3633 WP_023079718.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  CRD75_RS03075 (CRD75_03075) - 597361..598173 (+) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  CRD75_RS03080 (CRD75_03080) rpsU 598314..598490 (+) 177 WP_000048058.1 30S ribosomal protein S21 -
  CRD75_RS03085 (CRD75_03085) mscL 598618..598980 (-) 363 WP_002990299.1 large conductance mechanosensitive channel protein MscL -
  CRD75_RS03090 (CRD75_03090) dnaG 599110..600924 (+) 1815 WP_011284666.1 DNA primase -
  CRD75_RS03095 (CRD75_03095) rpoD 600933..602042 (+) 1110 WP_002985187.1 RNA polymerase sigma factor RpoD -

Sequence

Protein


Download         Length: 1210 a.a.        Molecular weight: 138991.17 Da        Isoelectric Point: 6.5805

>NTDB_id=208569 CRD75_RS03070 WP_023079718.1 593589..597221(+) (rexA) [Streptococcus pyogenes strain HarveyGAS]
MISFAPFLSPEAIKHLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTF
TVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLGQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVL
KQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHD
IELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDV
TVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDITHFAIKILEENTDI
RQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENF
RSQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAK
EIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYSIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRS
PMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPELIHDTLLGKLNIFLKTLKSWRRYAKLGSLYDLIWKIFN
DRFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQ
FPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYV
AMTRAEKKVYFIGKASKSKSQDITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKVAYEPLLEPIGVDIIEKSSRSLSDFTL
PHFSKKVKVEASHIGSALHQLMQVLPLSKPINQQTLLDALREIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYR
EAPFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLM
GGGKPEIVEV

Nucleotide


Download         Length: 3633 bp        

>NTDB_id=208569 CRD75_RS03070 WP_023079718.1 593589..597221(+) (rexA) [Streptococcus pyogenes strain HarveyGAS]
GTGATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTGCAGTGATCAGTCTCA
AAAACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAA
AAACCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTT
ACTGTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCA
AATGAAAGTTTATTTAACAGAACAATTGCAATCTCTTGGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAG
TAGTAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTA
AAGCAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCAAAAAGAGGCACCGGTGTTTAGGGCTCTTGTGAAAAA
TTTTTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAA
ATCCAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGGCTTGAAGATATCCCGGATCATGAT
ATTGAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCT
GACTAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATT
TTAAATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGGCCTTATACCATCTGGGAATGATGTT
ACAGTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTT
AATGTATCAGAAAGACTGTTTTCCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTG
TCAAAATACAAGAAAGTGCTTTTGAATTTTCAGATATTACACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATT
CGCCAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCT
GACCTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATC
CTCAGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTT
CGTAGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATA
CGATGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTAT
ATAATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAA
GAAATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGA
TATCATTTCTCATACATTCAATCAATATAGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTG
AAGTGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCA
CCGATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATA
TGACAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTCATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATA
TTTTTTTAAAGACGTTGAAAAGTTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTTAAT
GATCGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACG
TGCTAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAA
ATGACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAA
TTTCCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCA
GCACGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCA
TGGAAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTATTGTATGTT
GCTATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGATATCACAGATCCTAA
AAAGTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATA
TATTTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTT
CAAACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTT
AGAAGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGG
TAGCTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTG
CCACATTTTTCAAAAAAAGTAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTT
GTCAAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGAAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTG
ATCTCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGA
GAAGCACCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTT
TTTGTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACC
AACAACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATG
GGAGGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD-like helicase C-terminal domain (UvrD_C)

(474-892)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1047-1197)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(30-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

48.366

100

0.489