Detailed information NTG0208192

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: BSL41_RS00815
• Genome accession: NZ_CP018347
• Coordinates: 127286..128323 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727280.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SWU02
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 122286..133323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSL41_RS00790	-	123025..124356 (-)	1332	WP_000390039.1	hemolysin family protein	-
BSL41_RS00795	endA	124647..125471 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
BSL41_RS00800	-	125510..125698 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
BSL41_RS00805	murA	125691..126974 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
BSL41_RS00810	-	126998..127228 (-)	231	WP_000615437.1	DUF1146 family protein	-
BSL41_RS00815	sepM	127286..128323 (-)	1038	WP_000727280.1	SepM family pheromone-processing serine protease	Regulator
BSL41_RS00820	coaD	128307..128795 (-)	489	WP_001280766.1	pantetheine-phosphate adenylyltransferase	-
BSL41_RS00825	rsmD	128785..129324 (-)	540	WP_000706960.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
BSL41_RS00830	asnA	129389..130381 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
BSL41_RS00840	-	130493..131176 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
BSL41_RS00845	-	131232..131972 (-)	741	WP_000152701.1	RNA methyltransferase	-
BSL41_RS00850	-	132006..132284 (+)	279	WP_001174613.1	acylphosphatase	-
BSL41_RS00855	yidC	132362..133288 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37567.60 Da
• Isoelectric Point: 5.0724

>NTDB_id=208192 BSL41_RS00815 WP_000727280.1 127286..128323(-) (sepM) [Streptococcus pneumoniae strain SWU02]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=208192 BSL41_RS00815 WP_000727280.1 127286..128323(-) (sepM) [Streptococcus pneumoniae strain SWU02]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAAATCATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGTCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.649	99.13	0.591