Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   LS838_RS09035 Genome accession   NZ_CP018217
Coordinates   1823041..1824843 (+) Length   600 a.a.
NCBI ID   WP_003613193.1    Uniprot ID   -
Organism   Lactobacillus delbrueckii subsp. allosunkii strain JCM 17838     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1804601..1847688 1823041..1824843 within 0


Gene organization within MGE regions


Location: 1804601..1847688
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LS838_RS08940 (LS838_08920) - 1804601..1805359 (-) 759 WP_050952941.1 C40 family peptidase -
  LS838_RS08945 (LS838_08925) - 1805652..1806365 (-) 714 WP_050952942.1 C40 family peptidase -
  LS838_RS08950 (LS838_08930) - 1806519..1807301 (-) 783 WP_050952943.1 C40 family peptidase -
  LS838_RS08955 (LS838_08935) - 1807489..1807962 (-) 474 WP_050952944.1 C40 family peptidase -
  LS838_RS08960 (LS838_08940) - 1808132..1809178 (-) 1047 WP_050952945.1 2-hydroxyacid dehydrogenase -
  LS838_RS08965 (LS838_08945) - 1809462..1809947 (-) 486 WP_003611214.1 C40 family peptidase -
  LS838_RS08970 (LS838_08950) - 1810055..1810597 (-) 543 WP_050952946.1 AAA family ATPase -
  LS838_RS08975 (LS838_08955) - 1810687..1811022 (+) 336 WP_050952947.1 DUF2187 family protein -
  LS838_RS08980 (LS838_08960) - 1811273..1812553 (-) 1281 WP_050952948.1 RNA-guided endonuclease TnpB family protein -
  LS838_RS08985 (LS838_08965) - 1812697..1814235 (+) 1539 WP_050952982.1 O-antigen ligase family protein -
  LS838_RS08990 (LS838_08970) - 1814288..1814914 (-) 627 WP_050952949.1 LVIS_2131 family protein -
  LS838_RS08995 (LS838_08975) - 1814917..1815432 (-) 516 WP_050952950.1 hypothetical protein -
  LS838_RS09000 (LS838_08980) - 1815922..1816356 (+) 435 WP_231115348.1 hypothetical protein -
  LS838_RS09005 (LS838_08985) - 1816582..1817073 (-) 492 WP_003621154.1 threonine/serine exporter family protein -
  LS838_RS09010 (LS838_08990) - 1817076..1817831 (-) 756 WP_050952952.1 threonine/serine exporter family protein -
  LS838_RS09015 (LS838_08995) - 1817884..1819428 (-) 1545 WP_050952953.1 ABC-F family ATP-binding cassette domain-containing protein -
  LS838_RS09020 (LS838_09000) - 1819443..1819820 (-) 378 WP_002879494.1 hypothetical protein -
  LS838_RS09025 (LS838_09005) - 1819939..1821078 (-) 1140 WP_050952954.1 LCP family protein -
  LS838_RS09030 - 1821420..1822718 (+) 1299 Protein_1702 transposase -
  LS838_RS09035 (LS838_09020) pepF 1823041..1824843 (+) 1803 WP_003613193.1 oligoendopeptidase F Regulator
  LS838_RS09040 (LS838_09025) - 1824913..1826139 (-) 1227 WP_050952955.1 lactate oxidase -
  LS838_RS09045 (LS838_09030) - 1826269..1827807 (-) 1539 WP_050952956.1 L-lactate permease -
  LS838_RS10580 - 1828061..1828414 (-) 354 WP_050952957.1 hypothetical protein -
  LS838_RS09050 (LS838_09035) - 1828542..1829339 (-) 798 WP_003621140.1 metal ABC transporter permease -
  LS838_RS09055 (LS838_09040) - 1829339..1829992 (-) 654 WP_050952958.1 ATP-binding cassette domain-containing protein -
  LS838_RS09060 (LS838_09045) - 1830018..1830818 (-) 801 WP_050952983.1 HAD family hydrolase -
  LS838_RS09065 (LS838_09050) - 1831074..1833044 (-) 1971 WP_003613262.1 fructose-specific PTS transporter subunit EIIC -
  LS838_RS09070 (LS838_09055) pfkB 1833093..1834007 (-) 915 WP_003613184.1 1-phosphofructokinase -
  LS838_RS09075 (LS838_09060) - 1834007..1834756 (-) 750 WP_050952959.1 DeoR/GlpR family DNA-binding transcription regulator -
  LS838_RS09085 (LS838_09070) - 1834919..1835668 (-) 750 WP_003613284.1 amino acid racemase -
  LS838_RS09090 (LS838_09075) - 1835682..1837232 (-) 1551 WP_003613272.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase -
  LS838_RS09095 (LS838_09080) - 1837269..1838468 (-) 1200 WP_050952960.1 HAMP domain-containing sensor histidine kinase -
  LS838_RS09100 (LS838_09085) - 1838458..1839144 (-) 687 WP_050952961.1 response regulator transcription factor -
  LS838_RS09105 (LS838_09090) - 1839273..1841117 (-) 1845 WP_050952962.1 ABC transporter ATP-binding protein -
  LS838_RS09110 (LS838_09095) - 1841128..1842855 (-) 1728 WP_050952963.1 ABC transporter ATP-binding protein -
  LS838_RS09115 (LS838_09100) - 1842994..1843764 (-) 771 WP_002879518.1 DUF1129 domain-containing protein -
  LS838_RS09120 (LS838_09105) ychF 1843779..1844879 (-) 1101 WP_050952964.1 redox-regulated ATPase YchF -
  LS838_RS09125 (LS838_09110) - 1844956..1845219 (-) 264 WP_050952965.1 DUF951 domain-containing protein -
  LS838_RS09130 (LS838_09115) - 1845212..1846105 (-) 894 WP_050952966.1 ParB/RepB/Spo0J family partition protein -
  LS838_RS09135 (LS838_09120) - 1846083..1846862 (-) 780 WP_002879524.1 AAA family ATPase -
  LS838_RS09140 (LS838_09125) noc 1846864..1847688 (-) 825 WP_002879525.1 nucleoid occlusion protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 68245.96 Da        Isoelectric Point: 4.4594

>NTDB_id=207361 LS838_RS09035 WP_003613193.1 1823041..1824843(+) (pepF) [Lactobacillus delbrueckii subsp. allosunkii strain JCM 17838]
MESPYRSEVPKEQTWDLTRVFKTEADWEAAFKAVKQEIKALPALEDGFTESAAVLYDRLTQIFAVDRRLSKIYVYASMAS
DVDTSNQKKLALNSRGQSLAAEYQAAVAFIQPAVLALGKEGLDAFFKEEPRLENYRHYLEQIVKQEEHVLPAEEEKLVSA
AGDALSASANTFNVLTNSDLQFPYIEDEDGEAVELTEANYDILIQSQNREVREDAFDALYAGYGQFASTFASTLAGNVKA
HNFDAQTHHYQDALAAALSENNIPVDVYNQLLTSVHKHLDLLHRYVNLREEILDLKGDLQMWDMYVPITGKPSLSYTFAE
AKAQAREALQVLGEDYVKHVDYLFNNRCIDHVANMHKQSGAYSGGAYDTDAYELLNWQGDLDSLYTLVHETGHSVHSMYT
RENQPYVYGDYPIFVAEIASTTNENLLTNYFLDRVTDPKTRAFLLNYYLSSFKGTVYRQTQFAEFEKFIHESDQAGEALT
ADYLCGFYDRLNQQYYGPAISLGSDIDLEWARIPHFYYNFYVYQYATGFAAATALANKITYGSQEDKEKYLDFLKSGSSD
YPINIMQKAGVDMTKSDYLEDAFKVFAERLDEFTDLIKKL

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=207361 LS838_RS09035 WP_003613193.1 1823041..1824843(+) (pepF) [Lactobacillus delbrueckii subsp. allosunkii strain JCM 17838]
ATGGAAAGCCCTTATCGCAGTGAGGTTCCCAAAGAACAGACCTGGGACTTGACCCGGGTCTTCAAGACTGAGGCGGACTG
GGAGGCCGCCTTTAAAGCAGTCAAGCAGGAAATCAAGGCCCTGCCGGCCTTGGAAGACGGCTTTACGGAGAGCGCGGCCG
TCCTCTATGACCGCTTGACCCAGATTTTTGCCGTTGACCGCCGCCTGTCCAAGATCTACGTCTATGCCAGCATGGCCAGC
GACGTCGACACCAGCAACCAGAAGAAGCTGGCCCTCAATTCTCGCGGCCAGAGCCTGGCCGCTGAATACCAGGCAGCTGT
TGCCTTCATTCAGCCGGCTGTTTTAGCCTTGGGGAAAGAGGGCCTGGACGCCTTTTTCAAGGAAGAGCCAAGACTGGAAA
ACTACCGGCACTATTTGGAACAGATCGTTAAGCAGGAAGAGCACGTTTTGCCAGCTGAAGAGGAGAAGCTGGTATCGGCG
GCCGGGGATGCCCTGTCAGCTTCGGCCAACACCTTCAACGTCTTGACCAACTCCGATTTGCAATTCCCTTACATTGAAGA
TGAAGACGGGGAAGCAGTGGAACTGACGGAAGCCAACTACGACATCTTGATCCAGTCCCAGAACCGGGAAGTCAGAGAGG
ACGCCTTTGACGCCCTTTACGCTGGCTACGGCCAGTTCGCGTCAACTTTTGCCTCAACCTTGGCCGGCAATGTCAAGGCC
CACAACTTTGATGCCCAGACCCACCACTACCAGGACGCCTTAGCCGCGGCTCTGTCAGAAAACAACATCCCTGTTGACGT
CTACAACCAGCTTTTGACTAGCGTCCACAAGCACCTGGACCTCCTCCACCGCTATGTCAACTTGCGCGAAGAGATCCTGG
ACCTGAAGGGCGACCTGCAAATGTGGGACATGTACGTGCCGATCACGGGCAAGCCAAGCCTCAGCTACACTTTCGCTGAA
GCCAAGGCCCAGGCCAGAGAGGCCCTGCAGGTTTTGGGCGAGGACTATGTCAAACACGTCGACTACCTCTTCAATAACCG
CTGCATCGACCACGTGGCTAACATGCACAAGCAAAGCGGGGCCTACTCCGGCGGGGCTTATGACACCGACGCCTATGAGC
TCTTGAACTGGCAGGGGGACCTAGATTCCCTCTACACCCTGGTCCACGAGACCGGCCACTCAGTCCACAGCATGTACACC
CGGGAAAACCAGCCATACGTGTACGGGGACTATCCGATTTTTGTCGCGGAAATTGCCTCAACGACCAATGAAAACCTGCT
GACCAACTACTTCCTGGACCGGGTGACGGATCCAAAGACCCGGGCCTTCCTGCTCAACTACTACTTGAGCTCCTTTAAGG
GAACGGTCTACCGGCAGACCCAGTTCGCAGAATTCGAGAAGTTCATTCATGAAAGCGACCAGGCGGGTGAAGCCTTGACG
GCTGACTACCTGTGCGGCTTCTACGACCGGCTCAACCAGCAGTACTACGGACCGGCGATCAGCCTGGGCAGCGACATCGA
CCTGGAATGGGCCCGGATCCCCCACTTCTATTACAACTTCTACGTCTACCAGTACGCGACCGGCTTTGCCGCGGCGACTG
CCCTGGCTAACAAGATTACTTACGGCAGCCAGGAAGACAAGGAGAAGTACCTGGACTTCCTTAAGTCCGGCTCCAGCGAC
TACCCGATCAACATCATGCAGAAGGCCGGCGTTGACATGACCAAGTCCGACTACCTGGAAGATGCCTTCAAGGTCTTTGC
GGAAAGACTGGACGAATTTACTGACTTAATCAAAAAATTGTAG

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(203-584)

Oligopeptidase F (Peptidase_M3_N)

(115-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.832

99

0.493

Multiple sequence alignment