Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   BSR30_RS11150 Genome accession   NZ_CP018205
Coordinates   2094712..2095428 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain HG001 isolate RN1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2089712..2100428
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR30_RS11115 - 2089931..2090557 (+) 627 WP_000522384.1 nitroreductase family protein -
  BSR30_RS11125 - 2090918..2091703 (+) 786 WP_000867960.1 carbon-nitrogen family hydrolase -
  BSR30_RS15450 hld 2092300..2092380 (-) 81 WP_000046022.1 delta-hemolysin -
  BSR30_RS11135 agrB 2092670..2093239 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  BSR30_RS11140 agrD 2093236..2093376 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  BSR30_RS11145 agrC 2093401..2094693 (+) 1293 WP_001554031.1 quorum-sensing sensor histidine kinase AgrC -
  BSR30_RS11150 agrA 2094712..2095428 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  BSR30_RS11155 - 2095500..2095607 (+) 108 WP_001790167.1 hypothetical protein -
  BSR30_RS11160 - 2095795..2096754 (-) 960 WP_001253312.1 carbohydrate kinase family protein -
  BSR30_RS11165 - 2096751..2098235 (-) 1485 WP_000141414.1 sucrose-6-phosphate hydrolase -
  BSR30_RS11170 - 2098384..2099334 (-) 951 WP_000790330.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=207258 BSR30_RS11150 WP_000688492.1 2094712..2095428(+) (agrA) [Staphylococcus aureus strain HG001 isolate RN1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=207258 BSR30_RS11150 WP_000688492.1 2094712..2095428(+) (agrA) [Staphylococcus aureus strain HG001 isolate RN1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment