Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   BSR19_RS03250 Genome accession   NZ_CP018187
Coordinates   635934..638204 (-) Length   756 a.a.
NCBI ID   WP_073687523.1    Uniprot ID   A0AB37D945
Organism   Streptococcus salivarius strain ICDC2     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 630934..643204
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS03225 (BSR19_03230) - 632547..633167 (+) 621 WP_048675996.1 DUF3862 domain-containing protein -
  BSR19_RS03230 (BSR19_03235) - 633250..633933 (+) 684 WP_156246558.1 TVP38/TMEM64 family protein -
  BSR19_RS03235 (BSR19_03240) - 634013..634975 (+) 963 WP_156246559.1 Gfo/Idh/MocA family protein -
  BSR19_RS03240 (BSR19_03245) - 635021..635323 (-) 303 WP_002885967.1 DUF1827 family protein -
  BSR19_RS03245 (BSR19_03250) - 635333..635791 (-) 459 WP_151404407.1 NUDIX hydrolase -
  BSR19_RS03250 (BSR19_03255) clpE 635934..638204 (-) 2271 WP_073687523.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  BSR19_RS03255 (BSR19_03260) argF 638447..639427 (+) 981 WP_156246560.1 ornithine carbamoyltransferase -
  BSR19_RS03260 (BSR19_03265) - 639496..639726 (+) 231 WP_002885970.1 DUF1797 family protein -
  BSR19_RS03265 (BSR19_03270) - 640041..640721 (+) 681 WP_002890385.1 amino acid ABC transporter permease -
  BSR19_RS03270 (BSR19_03275) - 640721..641455 (+) 735 WP_037602114.1 amino acid ABC transporter ATP-binding protein -
  BSR19_RS03275 (BSR19_03280) - 641627..642103 (+) 477 WP_064523218.1 ferrous iron transport protein A -

Sequence

Protein


Download         Length: 756 a.a.        Molecular weight: 83973.05 Da        Isoelectric Point: 5.0564

>NTDB_id=206842 BSR19_RS03250 WP_073687523.1 635934..638204(-) (clpE) [Streptococcus salivarius strain ICDC2]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQNCYKIMKSDPENPLNQFNQTGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGNTQGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPG
VGKTAVVEGLAQKIVDGSVPQKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNAG
DGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAI
TAAAELSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQ
KQTIKDQDMPVITEKHIEAIVEQKTNIPVGDLKEKEQSQLLSLADDLKSHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIG
SFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEV
EKAHPDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGATRENRTNSVLNQLGDFFSPEFMNRFD
GIIEFSALSKENLLTIVDLMLDNVNQRLANNGIHLSVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENPN
EKDLKAVMTSKGHITIKSAKKAEKATQKAEAAKESD

Nucleotide


Download         Length: 2271 bp        

>NTDB_id=206842 BSR19_RS03250 WP_073687523.1 635934..638204(-) (clpE) [Streptococcus salivarius strain ICDC2]
ATGCTCTGTCAAAACTGTAACCTTAATGAAGCTAGTATTCATTTGTATACCAATGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAAAATTGTTATAAAATCATGAAATCTGACCCAGAGAACCCCCTTAATCAATTCAATCAAACTGGAGGTTCCA
ACTTCTTCGATGATTTCTTCAGCGACCTAAATAACTTCCGTTCTTCTAACGGTGATCTTCCCAATACACCTCCAACACAA
GAAGGTGGTAACCGAGGAAACGGTGGCAATACACAAGGGCCAGGCCGCCCAGGAGGACCACGCCAACAAGCTCCTCAACA
GCCACAAGGTCTTCTTGAAGAGTTCGGCATTAACATCACTGACATCGCTCGTCGTGGAGACATCGATCCAGTCATTGGTC
GTGACGAGGAAATCATTCGTGTCATCGAAATTCTTAACCGCCGTACCAAGAACAATCCCGTCCTCATCGGTGAACCCGGT
GTCGGTAAGACTGCTGTCGTTGAAGGACTAGCTCAAAAAATTGTAGATGGTAGCGTTCCTCAAAAACTCCAAGGCAAACA
AGTTATCCGTCTTGATGTGGTCAGCTTGGTTCAAGGAACTGGTATCCGTGGCCAATTTGAAGAACGCATGCAAAAACTTA
TGGAAGAAATTCGTCAACGTCAGGATGTTATCCTATTTATTGATGAAATTCATGAAATCGTAGGAGCTGGTAATGCTGGA
GATGGCAATATGGATGCTGGAAACATCCTAAAACCTGCCCTTGCTCGTGGGGAACTTCAACTGGTCGGAGCAACAACACT
CAACGAATACCGCATCATCGAAAAAGATGCTGCCCTTGAGCGTCGTATGCAACCAGTTAAGGTTGACGAACCAACTGTTG
AGGAAACCATCACTATTTTGCGTGGGATTCAGCCTAAATATCAAGACTACCACCACGTCAAATATACGGACGAAGCGATT
ACTGCAGCTGCAGAATTGTCCAACCGCTACATTCAAGACCGTTTCTTACCAGACAAGGCCATCGACCTTCTTGATGAAGC
TGGTTCGAAGATGAACTTGACCCTCAACTTTGTTGATCCTAAAGATATAGACAAACGTTTGATTGAGGCTGAAAACCTCA
AGGCTCAAGCTACTCGTGACGAGGACTTTGAAAAGGCTGCTTATTTCCGTGACCAAATTGCCAAATACAAGGAAATGCAA
AAGCAAACCATCAAAGACCAAGATATGCCTGTCATCACCGAAAAACATATCGAAGCTATTGTGGAACAAAAAACCAATAT
TCCTGTCGGTGATTTGAAAGAAAAAGAACAATCACAACTTCTTAGTCTTGCCGATGATCTTAAATCACATGTTATCGGAC
AAGATGCTGCAGTTGATAAGATTGCTAAAGCTATCCGCCGTAATCGTGTTGGATTGGGTGCTCCAAACCGCCCAATTGGT
AGCTTCCTCTTCGTAGGTCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAATTGGCTATTGAACTCTTTGGTTCAGC
TGACAGTATGATTCGTTTCGATATGTCAGAATACATGGAAAAACACGCTGTCGCTAAATTGGTTGGTGCCCCTCCAGGAT
ATGTTGGTTACGACGAAGCTGGTCAGTTAACTGAAAAAGTCCGCCGTAATCCTTATTCACTTATTCTTTTAGATGAGGTT
GAAAAAGCTCACCCAGACGTTCTTCACATGTTCCTCCAAGTACTTGACGACGGTCGTTTGACTGATGGACAAGGGCGCAC
TGTAAGCTTCAAGGATACCATCATCATCATGACCTCAAATGCTGGTACTGGTAAAGTTGAAGCTAGCGTTGGCTTTGGAG
CTACTCGTGAAAATCGTACCAATTCTGTTCTTAACCAACTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGCTTTGAT
GGTATTATCGAATTCTCTGCCCTCAGCAAAGAAAATCTCCTTACTATCGTGGACCTCATGCTTGATAATGTCAACCAACG
CTTGGCTAACAACGGTATCCACCTCAGTGTAACTGAGAAAGTTAAGGAAAAATTGGTTGACCTTGGTTACGATCCTAAGA
TGGGTGCTCGACCACTACGTCGTACCATCCAAGATCACATTGAAGATGCTATTACCGACTTCTACCTTGAAAATCCAAAC
GAAAAAGATCTCAAGGCAGTCATGACTTCAAAAGGCCACATTACCATTAAGTCTGCTAAAAAAGCCGAAAAAGCTACTCA
AAAAGCTGAGGCAGCAAAAGAATCTGATTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(154-274)

AAA domain (Cdc48 subfamily) (AAA_2)

(477-640)

AAA lid domain (AAA_lid_9)

(292-390)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(648-721)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.771

99.471

0.853
  clpE Streptococcus pneumoniae Rx1

83.134

99.603

0.828
  clpE Streptococcus pneumoniae D39

83.134

99.603

0.828
  clpE Streptococcus pneumoniae R6

83.134

99.603

0.828
  clpE Streptococcus pneumoniae TIGR4

83.134

99.603

0.828
  clpC Lactococcus lactis subsp. cremoris KW2

78.718

96.958

0.763
  clpC Bacillus subtilis subsp. subtilis str. 168

51.852

85.714

0.444
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.037

86.772

0.399
  clpC Streptococcus pneumoniae Rx1

47.36

82.672

0.392
  clpC Streptococcus pneumoniae D39

47.36

82.672

0.392
  clpC Streptococcus pneumoniae TIGR4

47.2

82.672

0.39
  clpC Streptococcus thermophilus LMD-9

47.04

82.672

0.389
  clpC Streptococcus thermophilus LMG 18311

46.72

82.672

0.386
  clpC Streptococcus mutans UA159

46.228

82.407

0.381

Multiple sequence alignment