Detailed information NTG0206823

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: BSR19_RS00525
• Genome accession: NZ_CP018187
• Coordinates: 85866..88316 (+)
• Length: 816 a.a.
• NCBI ID: WP_060973203.1
• Uniprot ID: A0AB37D7R0
• Organism: Streptococcus salivarius strain ICDC2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 80866..93316

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR19_RS00500 (BSR19_00500)	ahpC	81784..82344 (-)	561	WP_004182174.1	alkyl hydroperoxide reductase subunit C	-
BSR19_RS00505 (BSR19_00505)	rpsB	82617..83384 (+)	768	WP_002886342.1	30S ribosomal protein S2	-
BSR19_RS00510 (BSR19_00510)	tsf	83495..84535 (+)	1041	WP_002886343.1	translation elongation factor Ts	-
BSR19_RS00515 (BSR19_00515)	-	84641..85111 (-)	471	WP_060973202.1	COG2426 family protein	-
BSR19_RS00520 (BSR19_00520)	-	85410..85865 (+)	456	WP_002889615.1	CtsR family transcriptional regulator	-
BSR19_RS00525 (BSR19_00525)	clpC	85866..88316 (+)	2451	WP_060973203.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
BSR19_RS00530 (BSR19_00530)	pbp3	88445..89701 (-)	1257	WP_060973204.1	D-alanyl-D-alanine carboxypeptidase PBP3	-
BSR19_RS00535 (BSR19_00535)	pbp3	89846..91093 (-)	1248	WP_197092246.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90253.58 Da
• Isoelectric Point: 5.9166

>NTDB_id=206823 BSR19_RS00525 WP_060973203.1 85866..88316(+) (clpC) [Streptococcus salivarius strain ICDC2]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEAMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKSIHDLRKPKKSKASGNFANMMQPPQSSTGELADYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVAEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPKPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMVKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=206823 BSR19_RS00525 WP_060973203.1 85866..88316(+) (clpC) [Streptococcus salivarius strain ICDC2]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCTTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACCGCTGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCAGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGCTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTAACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGCATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGTCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAGTTGGCAGATTATACCAAGGACTTAACGGCAGTGGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAGATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTA
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTGGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGCT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGAGACTTCGAAGAACGTA
TGAATCAAATCATCGATGAGATTGAAGCTGATGGAAAAATCATTCTCTTTATTGACGAACTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGTACCTTAGATGCGGCAAATATTTTGAAACCTGCTCTAGCTCGTGGAACCCTTCATATGGTTGG
AGCTACCACTCAAGCAGAGTATCAAAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTAGCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAAGCAGTTGAGACAGCGGTCAAGGCGGCGCATCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGA
CCTTTTAGATGAAGCAAGTGCAACTGTTCAAGGTCGTATTAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAGGCTAGCCAAAAAGCAAAATTACCAAAACCTGCCTTG
GTAGATGCGGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATCCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTAAATCTGGAAGCAGAGCTTCACAAACGTGTTATTGGTCAAGACGAGGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGGCCTACTGGTGTTGGT
AAGACAGAATTGGCCAAGGCATTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGATATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGACTTAACGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTTGACTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTGTTGGTTTTGGAGTCCAAGACATTTCTCATAATCACCAAG
CTATGCAGTCACGTATCATGGAAGAACTTAAGAAGGCCTACCGCCCAGAGTTTATCAACCGTATTGATGAAAAGGTTGTC
TTCCATAGCCTAGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGGTAAAACCGTTGGTTTCAGCTTTGGCAGAAAA
AGGAATTGACTTAAAATTCCAACCAGCTGCTCTCAAGCATTTGGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGCCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (377-457)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (108-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-46)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-370)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMG 18311	95.343	100	0.953
clpC	Streptococcus thermophilus LMD-9	95.221	100	0.952
clpC	Streptococcus mutans UA159	72.917	100	0.729
clpC	Streptococcus pneumoniae TIGR4	67.279	100	0.673
clpC	Streptococcus pneumoniae Rx1	67.279	100	0.673
clpC	Streptococcus pneumoniae D39	67.279	100	0.673
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.301	100	0.512
clpC	Bacillus subtilis subsp. subtilis str. 168	47.509	100	0.479
clpE	Streptococcus mutans UA159	48.083	76.716	0.369