Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   BSR14_RS02830 Genome accession   NZ_CP018186
Coordinates   556678..558558 (+) Length   626 a.a.
NCBI ID   WP_045768525.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC1     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 551678..563558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR14_RS02815 (BSR14_02820) fmt 553650..554585 (+) 936 WP_156209486.1 methionyl-tRNA formyltransferase -
  BSR14_RS02820 (BSR14_02825) rsmB 554575..555897 (+) 1323 WP_156209487.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  BSR14_RS02825 (BSR14_02830) - 555941..556678 (+) 738 WP_002886859.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BSR14_RS02830 (BSR14_02835) stkP/pknB 556678..558558 (+) 1881 WP_045768525.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BSR14_RS02835 (BSR14_02840) - 558703..559461 (+) 759 WP_156209489.1 potassium channel family protein -
  BSR14_RS02840 (BSR14_02845) liaF 559624..560322 (+) 699 WP_002886862.1 cell wall-active antibiotics response protein LiaF -
  BSR14_RS02845 (BSR14_02850) - 560319..561329 (+) 1011 WP_045768527.1 sensor histidine kinase -
  BSR14_RS02850 (BSR14_02855) - 561319..561963 (+) 645 WP_002884791.1 response regulator transcription factor -
  BSR14_RS02865 (BSR14_02870) rimM 562658..563176 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 68189.95 Da        Isoelectric Point: 7.6981

>NTDB_id=206779 BSR14_RS02830 WP_045768525.1 556678..558558(+) (stkP/pknB) [Streptococcus salivarius strain ICDC1]
MIQVGKLFAGRYRILKAIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEILSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGRIPYDGDSAVTIALQHFQKPLPSILAENHNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLYPSHSRDAKVVFDDMTDTKTLPKVTPVPSVSSEKKATAKSSESKQAV
SKQPRKNSTLAKNKKKKKKKSFFSTSLKVFLGLVFIGIIIFAYLVFTNPDSTQVPNVVGQELSTAQTKIEGAGFKVGEVK
EMEDDSVDTGKVVKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEE
GEILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSST
EVLYQDPQAGISVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTESTSSSTETPTEATHTDQQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=206779 BSR14_RS02830 WP_045768525.1 556678..558558(+) (stkP/pknB) [Streptococcus salivarius strain ICDC1]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAAGCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATCTTGGATAATGAGAAAGTGGCCATTAAGGTGCTTCGTACTAATTATCAAACCGATCAGGTAG
CTGTGGCACGTTTCCAGCGTGAAGCACGTGCCATGGCAGAACTCAGTCATCCCAATATCGTTGCAATCCGAGACATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTACGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATTATGGGAGAGATTCTTTCTGCCATGACTCTTGCCCATCAAAAGGGTATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAAGACGGTAGGGCCAAAGTTACAGACTTCGGGATTGCGGTTGCC
TTTGCAGAGACTAGTTTGACTCAAACCAATTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCGCGTGGATC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGTATCATGCTCTTTGAAATGTTGACAGGGCGTATTCCATATGATG
GTGATAGTGCAGTTACCATCGCTCTTCAGCATTTCCAAAAACCATTACCATCAATCTTGGCTGAGAATCATAATGTTCCT
CAGGCATTGGAAAATGTGGTTATTCGAGCGACAGCTAAAAAGCTTGAAAATCGTTATAACAGTACTTTGGAAATGAGCCG
AGATTTAGTAACTAGCTTATATCCTAGCCATAGCCGTGATGCTAAGGTAGTCTTTGATGACATGACGGATACTAAGACTT
TGCCTAAGGTTACTCCAGTTCCGTCAGTAAGCTCTGAGAAAAAGGCAACTGCCAAGTCATCAGAGTCAAAACAAGCTGTA
AGTAAGCAACCAAGGAAAAATTCAACACTAGCTAAGAATAAAAAGAAGAAAAAAAAGAAAAGCTTTTTCTCGACATCACT
CAAGGTATTCCTGGGGTTGGTCTTTATCGGGATTATCATTTTTGCCTATTTGGTATTTACCAACCCTGATAGTACTCAGG
TGCCTAACGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAG
GAAATGGAAGATGACTCTGTCGATACAGGCAAGGTCGTAAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATC
AAGTATTGATATCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAGGGTAAAAACTATAAGGATGCCA
TTGAGGATTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAG
GGAGAAATCCTATCTCAAAGTCCAGGTAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGT
GGCAACTCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACTTTGAATCGTAAGA
GTATCTCAAGTAGTAGCATCGAGTATCATGACTATAATACTGGTGCTAAGTTAGACAAGGATAAGGTTCCTAGCAGCACA
GAGGTCCTTTATCAAGATCCACAAGCTGGTATAAGCGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAG
TTCAAGCCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGAAAGCACAAGCTCTAGTA
CTGAAACACCGACAGAGGCTACTCACACAGACCAACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(443-507)

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(513-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

92.823

100

0.93
  pknB Streptococcus mutans UA159

65.993

86.901

0.573
  stkP Streptococcus pneumoniae TIGR4

57.863

79.233

0.458
  stkP Streptococcus pneumoniae D39

57.661

79.233

0.457
  stkP Streptococcus pneumoniae R6

57.661

79.233

0.457
  stkP Streptococcus pneumoniae Rx1

57.46

79.233

0.455

Multiple sequence alignment