Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   BSR14_RS02255 Genome accession   NZ_CP018186
Coordinates   426919..428724 (+) Length   601 a.a.
NCBI ID   WP_045772175.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC1     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 423657..436919 426919..428724 within 0


Gene organization within MGE regions


Location: 423657..436919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR14_RS02245 (BSR14_02245) - 423657..424676 (+) 1020 WP_171021848.1 IS30-like element IS1139 family transposase -
  BSR14_RS02250 (BSR14_02250) - 425949..426908 (+) 960 WP_014633524.1 competence protein CoiA -
  BSR14_RS02255 (BSR14_02255) pepF 426919..428724 (+) 1806 WP_045772175.1 oligoendopeptidase F Regulator
  BSR14_RS02260 (BSR14_02260) - 428937..430157 (+) 1221 WP_014633522.1 OFA family MFS transporter -
  BSR14_RS02265 (BSR14_02265) - 430229..430936 (+) 708 WP_002886734.1 O-methyltransferase -
  BSR14_RS02270 (BSR14_02270) - 430998..432140 (+) 1143 WP_045772176.1 peptidyl-prolyl cis-trans isomerase -
  BSR14_RS02275 (BSR14_02275) - 432479..432964 (+) 486 WP_045772177.1 LURP-one-related/scramblase family protein -
  BSR14_RS02280 (BSR14_02280) alaS 432989..435607 (+) 2619 WP_014633520.1 alanine--tRNA ligase -
  BSR14_RS02285 (BSR14_02285) tnpA 435799..436215 (+) 417 WP_002886752.1 IS200/IS605 family transposase -
  BSR14_RS02290 (BSR14_02290) - 436533..436919 (+) 387 WP_045772178.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69058.09 Da        Isoelectric Point: 4.5615

>NTDB_id=206772 BSR14_RS02255 WP_045772175.1 426919..428724(+) (pepF) [Streptococcus salivarius strain ICDC1]
MSDNRAHLEEKYTWDLTTIFATDADWETEYESTVQDLKKASAYAGHLLDSAKNLLEATELYMSLMRRLEKIYVYASMKND
QDTTVGLYQEYQAKASNLYSQLSEAFAYFEPEFMALDDKKLAEFKEQEPGLGLYDHYFERLLANKDHVLSQEAEELLAAA
GDIFNGPTDTFNVLDNADILFPWVSDGQGDVVELTHGNFITLMESKDRDIRKGAYEAMYGTYEQFQHTYAQTLQGVVKVH
NYQAKVRHYNSARHAALAANFIPESVYDSLLESVNKHLPLLHRYLDLRKKVLGLDELKMYDVYTPLSETETALTYEESLK
KAEEVLAIFGEEYSKGVHAAFTERWIDVHPNKGKRSGAYSGGAYDTNAFMLLNWQDTLDNLFTLVHETGHSLHSTFTRQT
QPYVYGDYSIFLAEIASTTNENILTETLLKEVKDDKTRFAILNHYLDGFKGTVFRQTQFAEFEHAIHEADASGQILTADF
MNKLYADLNEKYYNLKAEDNYEIQFEWERIPHFYMNYYVYQYATGFAAASYLAEKIVHGTEEDKEAYLTYLKAGSSDYPL
EVIKKAGVDMTNTDYLDAAFKVFEDRLVELEVLVEKGVHLS

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=206772 BSR14_RS02255 WP_045772175.1 426919..428724(+) (pepF) [Streptococcus salivarius strain ICDC1]
ATGTCAGACAATCGTGCTCATTTAGAAGAGAAATACACATGGGATTTGACGACCATTTTTGCGACAGATGCAGATTGGGA
GACTGAATATGAAAGCACTGTTCAGGATTTGAAGAAGGCTAGTGCTTATGCAGGTCATCTCTTAGATTCTGCTAAGAACT
TGCTTGAGGCAACTGAACTTTATATGAGTCTTATGCGTCGCTTGGAGAAAATCTATGTCTATGCGTCAATGAAAAATGAC
CAAGACACAACAGTAGGTCTTTACCAAGAGTACCAAGCTAAGGCCTCAAACCTTTACTCACAGTTGAGTGAAGCCTTTGC
TTACTTTGAGCCTGAATTTATGGCCTTGGATGATAAGAAATTAGCTGAATTTAAAGAACAAGAGCCAGGTCTTGGACTTT
ATGATCACTATTTCGAACGTCTTTTGGCAAACAAGGACCACGTTCTTTCTCAAGAAGCTGAAGAGCTCTTGGCAGCAGCC
GGTGATATTTTCAACGGCCCAACGGATACCTTCAATGTCTTGGATAATGCTGATATCCTCTTCCCATGGGTATCAGATGG
TCAAGGGGATGTGGTTGAGTTGACACATGGTAACTTTATCACTCTCATGGAATCTAAGGACCGTGACATTCGTAAGGGAG
CTTATGAAGCGATGTACGGTACTTATGAGCAGTTCCAACATACTTATGCACAAACACTCCAAGGCGTTGTCAAGGTTCAC
AATTACCAAGCCAAAGTTCGTCACTATAATTCAGCACGTCATGCAGCACTTGCGGCTAACTTTATTCCAGAGAGTGTTTA
TGACTCACTCTTGGAATCAGTGAACAAGCATTTGCCACTTTTGCATCGTTACCTTGATTTGCGTAAGAAGGTCTTGGGGC
TTGACGAGCTTAAGATGTATGACGTCTATACACCACTTTCTGAGACTGAAACTGCTCTTACTTATGAAGAATCCCTCAAG
AAAGCAGAAGAAGTCTTGGCAATCTTTGGTGAAGAGTATAGTAAAGGGGTTCATGCAGCCTTTACGGAACGTTGGATTGA
CGTTCACCCTAACAAAGGAAAACGTTCAGGTGCCTACTCAGGTGGTGCTTATGATACCAATGCCTTCATGCTTTTGAACT
GGCAAGATACTTTGGACAATCTCTTTACCTTGGTTCACGAGACTGGCCACAGTTTGCATTCAACGTTCACACGGCAGACT
CAACCATATGTTTACGGAGATTACTCAATCTTCTTGGCAGAAATTGCGTCTACAACCAATGAAAATATCTTGACAGAAAC
GCTTCTTAAAGAGGTCAAAGATGACAAGACACGTTTTGCTATTCTTAACCACTATCTGGATGGTTTCAAGGGAACTGTCT
TCCGTCAAACACAATTTGCCGAGTTTGAACATGCTATTCATGAGGCAGATGCATCTGGTCAAATCTTGACAGCGGACTTC
ATGAATAAGCTTTACGCAGACCTCAATGAGAAATACTATAACCTTAAAGCTGAAGATAACTACGAAATTCAGTTTGAGTG
GGAACGTATTCCGCATTTCTACATGAACTACTATGTCTACCAATACGCTACAGGATTTGCTGCGGCAAGCTACTTGGCTG
AAAAAATTGTTCACGGTACTGAAGAAGATAAAGAAGCTTACCTTACTTACCTTAAGGCAGGAAGCTCAGACTATCCTTTG
GAAGTCATCAAGAAAGCTGGTGTTGATATGACCAATACCGACTACTTAGATGCTGCCTTCAAAGTTTTTGAAGACCGTCT
CGTTGAATTGGAAGTCTTGGTTGAAAAAGGTGTTCACCTTTCGTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

99.334

100

0.993

Multiple sequence alignment