Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BSR08_RS02510 Genome accession   NZ_CP018184
Coordinates   479702..480358 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain KH2     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 474702..485358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR08_RS02485 (BSR08_02500) oppF 475166..476083 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  BSR08_RS02490 (BSR08_02505) yjbB 476191..477408 (+) 1218 WP_072592593.1 MFS transporter -
  BSR08_RS02495 (BSR08_02510) yjbC 477572..478150 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  BSR08_RS02500 (BSR08_02515) spx 478331..478726 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  BSR08_RS02505 (BSR08_02520) yjbE 478769..479425 (-) 657 WP_014479447.1 TerC family protein -
  BSR08_RS22690 - 479595..479735 (+) 141 WP_119122854.1 hypothetical protein -
  BSR08_RS02510 (BSR08_02525) mecA 479702..480358 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  BSR08_RS22695 - 480353..480475 (-) 123 WP_003245684.1 hypothetical protein -
  BSR08_RS02515 (BSR08_02530) coiA 480519..481670 (+) 1152 WP_014479449.1 competence protein CoiA Machinery gene
  BSR08_RS02520 (BSR08_02535) pepF 481900..483729 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  BSR08_RS02525 (BSR08_02540) - 483767..483934 (-) 168 WP_003244944.1 hypothetical protein -
  BSR08_RS02535 (BSR08_02550) spxH 484249..485148 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=206682 BSR08_RS02510 WP_014479448.1 479702..480358(+) (mecA) [Bacillus subtilis strain KH2]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=206682 BSR08_RS02510 WP_014479448.1 479702..480358(+) (mecA) [Bacillus subtilis strain KH2]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment