Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   LMKH_RS11495 Genome accession   NZ_CP018149
Coordinates   2319463..2321268 (-) Length   601 a.a.
NCBI ID   WP_003724606.1    Uniprot ID   A0A3D7VFE2
Organism   Listeria monocytogenes strain VIMHA007     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2314463..2326268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMKH_RS11475 (LMKH_2253) isdE 2315386..2316258 (-) 873 WP_003727849.1 heme ABC transporter substrate-binding protein IsdE -
  LMKH_RS11480 (LMKH_2254) hbp2 2316345..2318054 (-) 1710 WP_003734378.1 hemin/hemoglobin-binding protein Hbp2 -
  LMKH_RS11485 (LMKH_2255) isdC 2318067..2318693 (-) 627 WP_003724604.1 heme uptake protein IsdC -
  LMKH_RS11490 (LMKH_2256) - 2318904..2319164 (-) 261 WP_003724605.1 DUF3116 family protein -
  LMKH_RS11495 (LMKH_2257) pepF 2319463..2321268 (-) 1806 WP_003724606.1 oligoendopeptidase F Regulator
  LMKH_RS11500 (LMKH_2258) - 2321341..2322456 (-) 1116 WP_072219607.1 competence protein CoiA -
  LMKH_RS11505 (LMKH_2259) mecA 2322582..2323235 (-) 654 WP_003724608.1 adaptor protein MecA -
  LMKH_RS11510 (LMKH_2260) spxA 2323467..2323862 (-) 396 WP_003720569.1 transcriptional regulator SpxA -
  LMKH_RS11515 (LMKH_2261) - 2324182..2325150 (-) 969 WP_003722315.1 ABC transporter ATP-binding protein -
  LMKH_RS11520 (LMKH_2262) - 2325147..2326223 (-) 1077 WP_003722316.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 68550.63 Da        Isoelectric Point: 4.5488

>NTDB_id=206459 LMKH_RS11495 WP_003724606.1 2319463..2321268(-) (pepF) [Listeria monocytogenes strain VIMHA007]
MSKTNALPLREEVPENLTWDLTTIYPNDEAWEQAFTDLQKITEESEQFKGRLSESSQTLYEALQFRDNAYDLISNLYVYA
HLKMDQDTANAKYQGLHSRAGSLVTKLMSALSYYDPEILAMDESVLKQFLNENKDLQLYAHLLEELNLSRPYILSEKEEA
LLANAGEVLGSSSNTFNTLNNADMKFPTIKDENGEDIEITHGRFGKLLESNDPRVRREAFLGVYSVYEGLKNTLASTLNG
QVKKSNFYASTRGYTSAREAALSGNHIPETVYDSLLKSVNANADLLHRYVKLRKELLGLEELHMYDLYTPLSDDVNLEFT
YEEAKELVLEALKPLGDEYQAILKEAFDSRWIDVMENKGKRSGAYSSGSYSTSPYILLNWQDNINNVYTLAHELGHSVHS
YYTRKNQPFVYGDYSIFLAEVASTTNENLLTDYLLKKYDDPKVRAYLLNHYLDGFKGTVFRQTQFAEFEHAIHQADQEGV
ALTADYLTETYFDINKKYYGEAMVYDAEIGYEWSRIPHFYMNYYVFQYATGFSAASALSAKILTEGQEAVTAYIDFLKAG
SSDYPIDVLKKAGVDMATPNPVDDALKVFEQRLDELEKLVK

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=206459 LMKH_RS11495 WP_003724606.1 2319463..2321268(-) (pepF) [Listeria monocytogenes strain VIMHA007]
TTGAGTAAAACAAATGCATTACCTTTAAGAGAAGAAGTACCAGAAAATCTAACTTGGGATTTAACTACGATTTATCCAAA
CGATGAAGCTTGGGAACAAGCATTTACAGATTTGCAAAAAATCACAGAAGAAAGCGAGCAATTTAAAGGGCGTTTATCGG
AAAGCAGCCAGACACTATATGAAGCACTTCAATTTCGAGATAATGCATATGATTTAATTAGTAACTTATATGTATATGCG
CATTTGAAAATGGACCAAGATACAGCTAATGCGAAATATCAAGGTTTACATAGTCGCGCAGGAAGCCTAGTTACAAAGCT
AATGTCTGCACTGTCTTATTATGATCCTGAAATTTTAGCTATGGACGAAAGCGTTTTAAAACAATTTTTAAATGAGAACA
AAGATTTACAATTATATGCGCATTTACTAGAAGAGTTAAATTTAAGCCGACCGTATATTTTAAGTGAGAAAGAGGAGGCT
TTACTAGCTAACGCAGGTGAAGTGCTTGGCAGTTCGTCTAATACTTTTAATACCTTGAATAATGCAGATATGAAGTTTCC
AACCATTAAAGATGAGAACGGGGAAGATATCGAAATTACTCATGGTCGTTTCGGGAAATTGTTGGAAAGTAATGATCCGC
GAGTTCGTCGTGAAGCGTTTCTTGGTGTGTATTCTGTTTATGAAGGCCTAAAAAACACCTTAGCCTCTACTTTGAATGGA
CAAGTGAAGAAGTCTAATTTTTATGCTTCCACTCGTGGCTACACGTCAGCTCGTGAAGCGGCTCTTTCTGGGAACCATAT
TCCTGAAACAGTATATGATTCCTTGTTAAAATCAGTAAATGCGAATGCAGATTTGCTTCATCGTTATGTGAAGTTACGTA
AAGAATTACTTGGCTTAGAGGAATTGCATATGTATGATCTTTATACGCCACTTTCTGATGATGTTAATTTGGAGTTTACT
TATGAAGAAGCGAAAGAACTTGTGCTTGAAGCGCTTAAACCGCTTGGTGATGAATATCAAGCAATTTTAAAAGAAGCATT
TGATAGTCGTTGGATTGATGTGATGGAAAATAAAGGAAAACGTAGTGGAGCCTATTCTTCTGGTTCGTATAGTACGAGTC
CTTATATTTTACTCAATTGGCAGGATAATATTAACAATGTTTACACACTTGCGCATGAATTAGGGCATAGTGTGCATAGT
TATTATACAAGAAAAAACCAACCATTTGTTTATGGTGATTATTCGATTTTCTTAGCGGAGGTTGCTTCGACAACAAATGA
AAATTTACTAACTGATTATCTTCTTAAGAAATATGATGATCCAAAAGTTCGTGCTTACTTGTTGAATCACTATTTGGATG
GATTCAAGGGTACTGTATTCCGTCAAACCCAATTTGCTGAATTTGAACATGCTATTCATCAAGCGGATCAAGAAGGAGTG
GCGCTGACTGCGGATTACTTGACCGAAACATATTTTGATATTAACAAGAAATATTACGGAGAAGCGATGGTTTATGATGC
TGAAATCGGTTATGAATGGTCTCGTATTCCGCATTTTTATATGAATTATTATGTGTTCCAATATGCGACTGGTTTTTCTG
CAGCATCTGCATTGAGTGCGAAGATTTTAACAGAAGGCCAAGAAGCGGTGACTGCCTATATTGATTTCTTGAAAGCGGGA
AGTTCGGATTATCCTATCGATGTGTTGAAAAAAGCAGGAGTTGATATGGCAACTCCTAATCCGGTGGATGATGCACTAAA
AGTATTTGAACAAAGATTAGATGAACTAGAAAAATTAGTTAAATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-586)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3D7VFE2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.014

98.502

0.503

Multiple sequence alignment