Detailed information NTG0206085

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: BMJ42_RS10550
• Genome accession: NZ_CP018136
• Coordinates: 1906845..1907882 (-)
• Length: 345 a.a.
• NCBI ID: WP_073177337.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SP49
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1901845..1912882

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BMJ42_RS10525 (BMJ42_01997)	-	1902584..1903915 (-)	1332	WP_000390044.1	hemolysin family protein	-
BMJ42_RS10530 (BMJ42_01998)	endA	1904206..1905030 (-)	825	WP_001036785.1	DNA-entry nuclease EndA	Machinery gene
BMJ42_RS10535 (BMJ42_01999)	-	1905069..1905257 (-)	189	WP_001036519.1	DNA-directed RNA polymerase subunit beta	-
BMJ42_RS10540 (BMJ42_02000)	murA	1905250..1906533 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
BMJ42_RS10545 (BMJ42_02001)	-	1906557..1906787 (-)	231	WP_000250391.1	DUF1146 family protein	-
BMJ42_RS10550 (BMJ42_02002)	sepM	1906845..1907882 (-)	1038	WP_073177337.1	SepM family pheromone-processing serine protease	Regulator
BMJ42_RS10555 (BMJ42_02003)	coaD	1907866..1908354 (-)	489	WP_001280746.1	pantetheine-phosphate adenylyltransferase	-
BMJ42_RS10560 (BMJ42_02004)	rsmD	1908344..1908883 (-)	540	WP_000691938.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
BMJ42_RS10565 (BMJ42_02005)	asnA	1908948..1909940 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
BMJ42_RS10575 (BMJ42_02006)	-	1910053..1910736 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
BMJ42_RS10580 (BMJ42_02007)	-	1910792..1911532 (-)	741	WP_000152674.1	TrmH family RNA methyltransferase	-
BMJ42_RS10585 (BMJ42_02008)	-	1911566..1911844 (+)	279	WP_001174613.1	acylphosphatase	-
BMJ42_RS10590 (BMJ42_02009)	yidC	1911922..1912848 (+)	927	WP_000835944.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.57 Da
• Isoelectric Point: 5.0724

>NTDB_id=206085 BMJ42_RS10550 WP_073177337.1 1906845..1907882(-) (sepM) [Streptococcus pneumoniae strain SP49]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVSGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=206085 BMJ42_RS10550 WP_073177337.1 1906845..1907882(-) (sepM) [Streptococcus pneumoniae strain SP49]
ATGAAAAAAAAGATTAGATGGCCCTTGTATGTCATTGCGGCCTTGATTGTGACCTTCTTGGCATTTGTGGTGCCTTTGCC
CTACTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCTACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTTCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588