Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   BMJ42_RS05430 Genome accession   NZ_CP018136
Coordinates   954409..956211 (+) Length   600 a.a.
NCBI ID   WP_000244135.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SP49     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 949409..961211
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMJ42_RS05410 (BMJ42_01013) rnr 949704..952058 (+) 2355 WP_000654892.1 ribonuclease R -
  BMJ42_RS05415 (BMJ42_01014) smpB 952021..952488 (+) 468 WP_001051750.1 SsrA-binding protein SmpB -
  BMJ42_RS05420 (BMJ42_01015) tehB 952504..953364 (+) 861 WP_000413763.1 SAM-dependent methyltransferase TehB -
  BMJ42_RS05425 (BMJ42_01016) coiA 953437..954390 (+) 954 WP_000495910.1 competence protein CoiA Machinery gene
  BMJ42_RS05430 (BMJ42_01017) pepF 954409..956211 (+) 1803 WP_000244135.1 oligoendopeptidase F Regulator
  BMJ42_RS05435 (BMJ42_01018) - 956213..956926 (+) 714 WP_000230399.1 O-methyltransferase -
  BMJ42_RS05440 (BMJ42_01019) prsA 956993..957934 (+) 942 WP_000727952.1 peptidylprolyl isomerase PrsA -
  BMJ42_RS05445 - 958053..958382 (-) 330 Protein_1009 transposase -
  BMJ42_RS12660 - 958805..958900 (+) 96 Protein_1010 IS630 family transposase -
  BMJ42_RS05465 (BMJ42_01021) - 959153..959773 (-) 621 WP_000780818.1 histidine phosphatase family protein -
  BMJ42_RS05470 (BMJ42_01022) - 959773..960255 (-) 483 WP_001085885.1 aminoacyl-tRNA deacylase -
  BMJ42_RS05475 (BMJ42_01023) - 960255..961097 (-) 843 WP_000954122.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69867.77 Da        Isoelectric Point: 4.5450

>NTDB_id=206056 BMJ42_RS05430 WP_000244135.1 954409..956211(+) (pepF) [Streptococcus pneumoniae strain SP49]
MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYEGHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKND
QDTREAKYQEYYAKAMTLYSQLDQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQALYATYEQFQHTYAKTLQTNVKVQ
NYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRKHLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALK
KAEDALAVLGEDYLSRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSMHSSYTRET
QPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFRGTVFRQTQFAEFEHAIHQADQNGEVLTSDF
LNKLYADLNQEYYGLSKEDNPEIQYEWARIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPL
NVMRKAGVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=206056 BMJ42_RS05430 WP_000244135.1 954409..956211(+) (pepF) [Streptococcus pneumoniae strain SP49]
ATGGTATTACAAAGAAATGAAATAAATGAAAAAGATACATGGGATCTATCAACGATCTACCCAACTGACCAGGCTTGGGA
AGAAGCCTTAAAAGATTTAACAGAACAATTGGAGACAGTAGCCCAGTATGAAGGCCATCTCTTGGATAGTGCGGATAACC
TACTAGAAATCACTGAATTTTCTCTTGAAATGGAACGCCAGATGGAGAAGCTTTACGTTTATGCTCATATGAAGAATGAC
CAGGATACACGTGAAGCTAAGTATCAAGAGTACTATGCCAAGGCCATGACACTCTACAGCCAGTTAGACCAAGCCTTTTC
ATTCTATGATCCTGAATTTATGGAGATTAGCGAAAAGCAGTATGCTGACTTTTTAGAAGCTCAACCAAAGCTGCAGGTTT
ATCAACACTATTTTGACAAGCTCTTGCAAGGCAAGGATCACGTTCTTTCACAACGTGAAGAAGAATTATTGGCTGGAGCT
GGAGAAATCTTTGGTTCAGCAAGTGAAACCTTCGCTATCTTGGACAATGCGGATATTGTGTTCCCTTATGTCCTAGACGA
TGATGGTAAAGAAGTTCAGCTATCTCATGGGACTTACACACGTTTGATGGAGTCTAAAAAACGTGAGGTTCGCCGTGGTG
CCTATCAAGCTCTTTATGCGACTTACGAACAATTCCAACACACCTATGCCAAAACCTTGCAAACCAATGTTAAGGTGCAA
AATTACCGTGCTAAAGTTCGTAACTACAAGAGTGCTCGTCATGCAGCCCTCGCAGCGAATTTTGTTCCAGAAAGTGTTTA
TGACAATTTGGTAGCAGCAGTTCGCAAGCATTTGCCACTCTTACATCGCTATCTTGAGCTTCGTTCAAAAATCTTGGGGA
TTTCAGATCTCAAGATGTACGATGTCTACACACCGCTTTCATCTGTTGAATACAGTTTTACCTACCAAGAAGCCTTGAAA
AAAGCAGAAGATGCTTTGGCAGTCTTGGGTGAGGATTACTTGAGCCGTGTTAAACGTGCCTTCAGCGAGCGTTGGATTGA
TGTTTACGAAAATCAAGGCAAGCGTTCAGGTGCCTACTCTGGTGGTTCTTACGATACCAATGCCTTTATGCTTCTCAACT
GGCAAGACAATCTGGACAATCTCTTTACTCTTGTTCATGAAACAGGTCACAGTATGCATTCAAGCTATACTCGTGAAACT
CAGCCTTATGTTTACGGAGATTACTCTATCTTTTTGGCTGAGATTGCCTCAACTACCAATGAAAATATCTTGACGGAGAA
ATTATTGGAAGAAGTGGAAGACGACGCAACACGCTTTGCTATTCTCAATAACTTCCTAGATGGTTTCCGTGGAACAGTTT
TCCGCCAAACTCAATTTGCTGAGTTTGAACACGCCATTCACCAAGCAGATCAAAATGGGGAGGTCTTGACAAGCGATTTC
CTAAATAAACTCTACGCAGACTTGAACCAAGAGTATTATGGTTTGAGTAAGGAAGACAATCCTGAAATCCAATACGAGTG
GGCTCGCATTCCACACTTCTACTATAACTACTATGTATATCAATATTCAACTGGCTTTGCGGCCGCCTCAGCCTTGGCTG
AAAAAATTGTCCATGGTAGTCAAGAAGACCGTGACCGCTATATCGACTACCTCAAGGCAGGTAAGTCGGACTATCCACTT
AATGTCATGAGAAAAGCTGGTGTTGATATGGAGAAGGAAGACTACCTCAACGATGCCTTTGCAGTCTTTGAACGCCGTTT
AAATGAGTTTGAAGCCCTTGTTGAAAAATTAGGATTGGCATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

67.282

99.333

0.668

Multiple sequence alignment