Detailed information    

insolico Bioinformatically predicted

Overview

Name   pptA   Type   Regulator
Locus tag   BMJ42_RS03145 Genome accession   NZ_CP018136
Coordinates   541875..542606 (+) Length   243 a.a.
NCBI ID   WP_000889919.1    Uniprot ID   A0A062WNF5
Organism   Streptococcus pneumoniae strain SP49     
Function   export ComS (predicted from homology)   
Competence regulation

Genomic Context

Location: 536875..547606
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMJ42_RS03115 (BMJ42_00586) dnaK 537059..538882 (+) 1824 WP_000034662.1 molecular chaperone DnaK -
  BMJ42_RS03120 (BMJ42_00587) - 538884..539240 (+) 357 WP_000114422.1 hypothetical protein -
  BMJ42_RS03125 (BMJ42_00588) dnaJ 539642..540778 (+) 1137 WP_001066301.1 molecular chaperone DnaJ -
  BMJ42_RS03135 (BMJ42_00589) - 541100..541387 (-) 288 WP_000777760.1 hypothetical protein -
  BMJ42_RS03140 (BMJ42_00590) - 541397..541807 (-) 411 WP_001278301.1 HIT family protein -
  BMJ42_RS03145 (BMJ42_00591) pptA 541875..542606 (+) 732 WP_000889919.1 ABC transporter ATP-binding protein Regulator
  BMJ42_RS03150 (BMJ42_00592) - 542603..543652 (+) 1050 WP_073176713.1 ABC transporter permease -
  BMJ42_RS03155 (BMJ42_00593) - 543820..544149 (-) 330 WP_000132572.1 hypothetical protein -
  BMJ42_RS03160 (BMJ42_00594) - 544425..544763 (+) 339 WP_000682126.1 LytTR family DNA-binding domain-containing protein -
  BMJ42_RS03165 (BMJ42_00595) comE/blpR 544768..545505 (+) 738 WP_001219143.1 response regulator transcription factor Regulator
  BMJ42_RS03170 (BMJ42_00596) - 545519..546859 (+) 1341 WP_073176715.1 sensor histidine kinase -
  BMJ42_RS03175 (BMJ42_00597) blpC 546904..547059 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27012.49 Da        Isoelectric Point: 4.7737

>NTDB_id=206044 BMJ42_RS03145 WP_000889919.1 541875..542606(+) (pptA) [Streptococcus pneumoniae strain SP49]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EDL

Nucleotide


Download         Length: 732 bp        

>NTDB_id=206044 BMJ42_RS03145 WP_000889919.1 541875..542606(+) (pptA) [Streptococcus pneumoniae strain SP49]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTTCATGTTCCTGTTTTGAAAGATGTGTCCTTTACTGTTGAAAGTGG
GCAGTTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCAACGACGATCAATGAGATTATCGGTCTGTTGGCACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACTCTGCAAGGAGATGCGACTAGCTACCGCAAGCAGATTGGCTACATTCCT
GAGACGCCTAGTCTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCTATGGCTTACGGTATTGAGCAAAA
AGTGGCTTTCGAACGAGTAGAGCCCTTGTTAAAGATGTTCCGTCTGGACCAGAAATTAGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAGGTCATGATTATCTGTGCTTTTGTGGTGGATCCAAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTTGATCCGCTAGCTATTTCTGATTTGATTCAGCTTTTGGAAGTGGAGAAGCAAAAGGGCAAGTCTATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCCTTTGTCATTCTTCACAAGGGAGAGGTGCGTGCCAAAG
GCAATCTCCTGCAACTACGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACAAAAGAG
GAGGACCTATGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(17-160)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A062WNF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pptA Streptococcus salivarius strain HSISS4

72.614

99.177

0.72
  pptA Streptococcus thermophilus LMD-9

71.784

99.177

0.712

Multiple sequence alignment