Detailed information NTG0206011

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: BMJ37_RS17280
• Genome accession: NZ_CP018133
• Coordinates: 3499378..3500541 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain ATR2
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3494378..3505541

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BMJ37_RS17250 (BMJ37_16735)	-	3494643..3495062 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
BMJ37_RS17255 (BMJ37_16740)	comFC	3495136..3495825 (-)	690	WP_199449054.1	ComF family protein	Machinery gene
BMJ37_RS17260 (BMJ37_16745)	-	3495831..3496115 (-)	285	WP_003151389.1	late competence development ComFB family protein	-
BMJ37_RS17265 (BMJ37_16750)	comFA	3496173..3497558 (-)	1386	WP_029972824.1	DEAD/DEAH box helicase	Machinery gene
BMJ37_RS17270 (BMJ37_16755)	-	3497666..3498514 (-)	849	WP_003151387.1	DegV family protein	-
BMJ37_RS17275 (BMJ37_16760)	degU	3498612..3499301 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
BMJ37_RS17280 (BMJ37_16765)	degS	3499378..3500541 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
BMJ37_RS17285 (BMJ37_16770)	-	3500764..3501411 (+)	648	WP_007614107.1	YigZ family protein	-
BMJ37_RS17290 (BMJ37_16775)	-	3501416..3502630 (+)	1215	WP_014419013.1	LCP family protein	-
BMJ37_RS17295 (BMJ37_16780)	-	3502729..3503805 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
BMJ37_RS17300 (BMJ37_16785)	tuaH	3503938..3505134 (-)	1197	WP_029972825.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=206011 BMJ37_RS17280 WP_007407484.1 3499378..3500541(-) (degS) [Bacillus velezensis strain ATR2]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=206011 BMJ37_RS17280 WP_007407484.1 3499378..3500541(-) (degS) [Bacillus velezensis strain ATR2]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTCGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTGGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTTATCATTAAGGACAACGGAAAAGGTTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951