Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   DN94_09050 Genome accession   CP007565
Coordinates   1770626..1773199 (-) Length   857 a.a.
NCBI ID   AHX75756.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain 138spar     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1765626..1778199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DN94_09025 - 1765737..1766288 (-) 552 AHX75751.1 3-methyladenine DNA glycosylase -
  DN94_09030 ruvA 1766311..1766901 (-) 591 AHX75752.1 ATP-dependent DNA helicase RuvA Machinery gene
  DN94_09035 - 1766903..1768135 (-) 1233 AHX75753.1 MFS transporter -
  DN94_09040 hexB 1768167..1770140 (-) 1974 AHX75754.1 DNA mismatch repair protein MutL Machinery gene
  DN94_09045 - 1770366..1770569 (+) 204 AHX75755.1 cold-shock protein -
  DN94_09050 hexA 1770626..1773199 (-) 2574 AHX75756.1 DNA mismatch repair protein MutS Machinery gene
  DN94_09055 - 1773256..1773693 (-) 438 AHX75757.1 arginine repressor -
  DN94_09060 - 1773914..1775605 (+) 1692 AHX75758.1 arginine--tRNA ligase -
  DN94_09065 - 1775693..1776001 (+) 309 AHX75759.1 bacteriocin -
  DN94_09070 - 1776028..1776900 (-) 873 AHX75760.1 membrane protein -
  DN94_09075 - 1777008..1777952 (-) 945 AHX75761.1 tyrosyl-tRNA synthetase -

Sequence

Protein


Download         Length: 857 a.a.        Molecular weight: 96889.52 Da        Isoelectric Point: 4.7908

>NTDB_id=20596 DN94_09050 AHX75756.1 1770626..1773199(-) (hexA) [Streptococcus agalactiae strain 138spar]
MGKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLACMDVSTGEFQATLLTDFE
SVRSEILNLKAREMVVGCQLTDEKNHLLTKQMNLLLSYEDERLNDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQIPRIKMILQSFNQPELDIIVNKIDTMPELESLINTAIA
PEAQATITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEILEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENYHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHNRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIESGPADKSYGIHVAKIAGLPIDLLDRATDILSQLEADAVQLIVSAPQEA
VTADLNEEDSEKQQGQLSLFEELSNADRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide


Download         Length: 2574 bp        

>NTDB_id=20596 DN94_09050 AHX75756.1 1770626..1773199(-) (hexA) [Streptococcus agalactiae strain 138spar]
ATGGGGAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAGATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGAGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTCAAGCGTGAGGTAGT
GCAAGTTGTTACCCCAGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATGTATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGTGAAATACTAAATTTAAAAGCTCGTGAGATGGTAGTAGGATGTCAATTAACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTATCATACGAAGACGAACGACTTAATGATATTCATTTGATTGATGAGCAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTAGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACGAAAAATAGTCTAGATTTACTGGAGAATGC
TAGAACAAGCAAGAAGCACGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAACGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGCCTAGCAAGTCGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACAGACCTTATCACAAATTCCTCGGATTAAAATGATTTTACAGTCCTTTA
ATCAACCTGAGCTTGACATCATTGTCAACAAAATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGGCTACTATCACTGAGGGAAATATTATCAAGTCTGGATTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATCGGTACTCTTAAAATTG
ATTATAATAAAAAAGACGGTTATTACTTCCATGTTACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACATTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAATACTTGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCCCAAGTAGAATCTTATATTAAACGTCTTCAAGAGTTAG
CAAAGACGATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATTATCACTATGTTCGTCCAAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACTGTTGAAAAAGTGATGGGGGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTTTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGACGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCGAA
TCAAGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATAACCGTGTTAGGGCAAAAACAATGTTCGCGACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGACTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAATCTGGACCTGCGGATAAGTCTTATGGGATACACGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCAACTGATATTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCAGCCCCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAAGATTCTGAGAAGCAACAAGGACAATTATCGCTTTTTGAAGAACTTTCAAATGCAGA
TAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGATTTAA
AGAAATTATTATAA

Domains

Predicted by InterProScan.

MutS domain III (MutS_III)

(257-547)

MutS domain I (MutS_I)

(8-118)

MutS domain V (MutS_V)

(600-786)

MutS domain II (MutS_II)

(126-240)

MutS family domain IV (MutS_IV)

(416-506)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

68.728

100

0.687
  mutS Pseudomonas stutzeri strain ATCC 17587

36.697

100

0.373

Multiple sequence alignment