Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   CLD04_RS09850 Genome accession   NZ_CP023257
Coordinates   1872407..1874290 (+) Length   627 a.a.
NCBI ID   WP_041336024.1    Uniprot ID   -
Organism   Bacillus subtilis strain TLO3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1867407..1879290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CLD04_RS09835 (CLD04_09835) ymcA 1868444..1868875 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  CLD04_RS09840 (CLD04_09840) cotE 1869137..1869682 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  CLD04_RS09845 (CLD04_09845) hexA 1869815..1872391 (+) 2577 WP_041336021.1 DNA mismatch repair protein MutS Machinery gene
  CLD04_RS09850 (CLD04_09850) hexB 1872407..1874290 (+) 1884 WP_041336024.1 DNA mismatch repair endonuclease MutL Machinery gene
  CLD04_RS09855 (CLD04_09855) ymzD 1874690..1875145 (-) 456 WP_026113607.1 regulatory YrvL family protein -
  CLD04_RS09860 (CLD04_09860) - 1875300..1875857 (-) 558 WP_017694906.1 hypothetical protein -
  CLD04_RS09865 (CLD04_09865) pksA 1875978..1876592 (+) 615 WP_017694907.1 TetR/AcrR family transcriptional regulator -
  CLD04_RS09870 (CLD04_09870) - 1876731..1877087 (-) 357 WP_003231786.1 hypothetical protein -
  CLD04_RS09875 (CLD04_09875) - 1877166..1877990 (-) 825 WP_072557160.1 hypothetical protein -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70495.38 Da        Isoelectric Point: 5.5167

>NTDB_id=205772 CLD04_RS09850 WP_041336024.1 1872407..1874290(+) (hexB) [Bacillus subtilis strain TLO3]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPAEKKVPEKSTAPSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQEQTLEVSDVSAEEPETFEQECHEEEQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQEMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=205772 CLD04_RS09850 WP_041336024.1 1872407..1874290(+) (hexB) [Bacillus subtilis strain TLO3]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCTCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCTAGCAGGAAGGGAACCGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTGCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAGGAATTGCCTCCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGCAGAAGAGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
AGAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCACACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.497

100

0.467

Multiple sequence alignment