Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   BRL64_RS06860 Genome accession   NZ_CP018100
Coordinates   1321075..1323177 (-) Length   700 a.a.
NCBI ID   WP_081124313.1    Uniprot ID   -
Organism   Bacillus safensis strain BRM1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1316075..1328177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BRL64_RS06830 (BRL64_06710) - 1316492..1316734 (+) 243 WP_024424676.1 aspartyl-phosphate phosphatase Spo0E family protein -
  BRL64_RS06835 (BRL64_06715) - 1316781..1318286 (-) 1506 WP_034281538.1 ATP-binding protein -
  BRL64_RS06840 (BRL64_06720) - 1318491..1318946 (+) 456 WP_034281539.1 MarR family winged helix-turn-helix transcriptional regulator -
  BRL64_RS06850 (BRL64_06725) motB 1319140..1319910 (-) 771 WP_034281540.1 flagellar motor protein MotB -
  BRL64_RS06855 (BRL64_06730) motA 1319903..1320697 (-) 795 WP_024424680.1 flagellar motor stator protein MotA -
  BRL64_RS06860 (BRL64_06735) clpC 1321075..1323177 (-) 2103 WP_081124313.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  BRL64_RS06865 (BRL64_06740) - 1323422..1324465 (+) 1044 WP_081124314.1 hypothetical protein -
  BRL64_RS06870 (BRL64_06745) queC 1324741..1325397 (+) 657 WP_024424683.1 7-cyano-7-deazaguanine synthase QueC -
  BRL64_RS06875 (BRL64_06750) queD 1325398..1325838 (+) 441 WP_034281544.1 6-carboxytetrahydropterin synthase QueD -
  BRL64_RS06880 (BRL64_06755) queE 1325831..1326562 (+) 732 WP_034281545.1 7-carboxy-7-deazaguanine synthase QueE -
  BRL64_RS06885 (BRL64_06760) queF 1326578..1327075 (+) 498 WP_081124315.1 preQ(1) synthase -
  BRL64_RS06895 (BRL64_06770) - 1327553..1327909 (-) 357 WP_061109758.1 winged helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 700 a.a.        Molecular weight: 78015.67 Da        Isoelectric Point: 5.1221

>NTDB_id=205757 BRL64_RS06860 WP_081124313.1 1321075..1323177(-) (clpC) [Bacillus safensis strain BRM1]
MRCQHCQVNEATIRLNMQVNSSRRQMVLCEDCYTSLMEQSKMKMGPQLFGGSSFFSQAASHAPNMEQPKQKGLLDELGRN
LTDGANAGLIDPVIGRDEEVARVIEILNRRNKNNPVLIGEPGVGKTAIAEGLALKIASGDVPNKLKNKQIYLLDVSSLVA
NTGVRGQFEERMKQLIKELQSRKNIILFVDEIHLLVGAGSAEGSMDAGNILKPALARGELQLVGATTLKEYRQIEKDAAL
ERRFQPVIVDEPTQDEAIDILKGIQDKYEAYHGVTYSDEAIKACVQLSSRYIQDRHLPDKAIDLMDEAGSKANLSIDAAS
EDQLTNRLAQIAAEKQAALKEEQYEKAAKLRDEEEAIEARLQNKTTEKEHIVTAEDIQAIVEQKTGIPVGKLQADEQTKM
KEIDVRLKARVIGQEHAVDKVAKAVKRSRAGLKSKHRPTGSFLFVGPTGVGKTELSKTLAEELFGSRDAIIRLDMSEYME
KHSVSKLIGSPPGYVGHDEAGQLTEKVRRKPYSIILLDEIEKAHPDVQHMFLQIMEDGRLTDSQGRTVSFKDTVIIMTSN
AGSADKTVKVGFQSDQEEAIEEQSLIDSLSSYFKPEFLNRFDSIIQFESLDRDDLVKIVDLLLNELSEQLKEQNLTVHVT
NEAKEKIAELGYHPAFGARPLRRTIQEHVEDQMTEILLEEEQLSGFTVDVEHDEIVVKKG

Nucleotide


Download         Length: 2103 bp        

>NTDB_id=205757 BRL64_RS06860 WP_081124313.1 1321075..1323177(-) (clpC) [Bacillus safensis strain BRM1]
ATGCGTTGTCAACATTGTCAAGTAAATGAAGCAACTATTCGCCTGAATATGCAAGTAAATTCGTCCCGGCGCCAAATGGT
TTTATGTGAAGACTGCTATACCTCTTTGATGGAGCAGTCAAAAATGAAAATGGGACCTCAGCTTTTTGGAGGAAGTTCAT
TCTTCTCTCAGGCAGCAAGTCATGCCCCAAACATGGAGCAGCCAAAGCAAAAAGGCTTACTCGATGAGCTTGGCCGTAAC
TTAACAGATGGAGCAAATGCTGGTTTAATTGATCCAGTCATTGGCCGAGATGAAGAAGTCGCAAGAGTCATTGAGATTTT
AAATAGAAGAAATAAAAATAACCCTGTTCTTATTGGTGAACCTGGTGTTGGGAAAACAGCGATCGCAGAAGGACTCGCGC
TCAAAATTGCGAGCGGCGATGTGCCAAATAAATTAAAGAACAAACAAATCTATTTATTAGATGTCTCCTCACTTGTCGCA
AACACAGGTGTACGCGGTCAATTTGAGGAAAGAATGAAGCAGTTAATCAAAGAACTGCAAAGCCGTAAAAATATCATCTT
ATTTGTAGATGAAATCCACCTTCTTGTGGGCGCAGGATCTGCAGAAGGATCAATGGATGCTGGAAACATTTTAAAACCAG
CACTTGCAAGAGGCGAGCTGCAGCTAGTAGGTGCGACGACATTAAAAGAATATCGCCAAATTGAAAAAGATGCTGCACTC
GAACGGCGCTTCCAGCCCGTTATCGTAGATGAGCCAACACAAGATGAAGCAATCGACATCTTAAAAGGCATTCAAGATAA
ATACGAGGCCTATCATGGTGTCACCTATTCAGATGAAGCAATCAAAGCGTGCGTTCAATTATCTTCGCGGTATATTCAAG
ACCGTCATTTGCCGGATAAAGCCATTGATTTAATGGATGAAGCTGGTTCAAAAGCGAACCTCTCCATTGATGCAGCAAGT
GAAGATCAGCTGACAAACCGACTAGCGCAAATTGCCGCAGAAAAACAAGCTGCGCTAAAAGAAGAACAATATGAAAAAGC
AGCGAAGCTACGCGATGAAGAAGAAGCCATTGAAGCAAGACTTCAAAACAAAACAACTGAAAAAGAGCATATCGTTACAG
CAGAGGACATTCAGGCCATTGTGGAACAAAAAACAGGCATTCCTGTCGGGAAACTCCAAGCAGACGAACAAACCAAAATG
AAAGAAATTGACGTCCGTCTAAAAGCACGAGTGATTGGACAGGAACATGCGGTTGATAAAGTGGCGAAAGCCGTGAAAAG
AAGCAGAGCTGGTTTAAAATCGAAACATAGACCAACAGGCTCCTTCCTTTTCGTTGGACCAACAGGTGTCGGGAAAACCG
AATTGTCTAAAACGTTAGCTGAAGAATTATTCGGTTCAAGAGATGCGATCATTCGTTTAGATATGAGTGAGTACATGGAA
AAACACTCTGTGTCCAAACTCATCGGTTCTCCTCCTGGTTACGTTGGACATGATGAAGCTGGCCAGCTGACTGAAAAAGT
GCGCAGAAAACCATACAGCATCATTTTGCTGGATGAAATCGAAAAAGCACACCCAGATGTACAGCACATGTTCCTGCAAA
TCATGGAAGATGGCCGCTTAACAGACAGCCAAGGCAGAACGGTCAGCTTTAAAGATACAGTCATCATCATGACAAGTAAC
GCAGGCAGCGCAGATAAAACGGTCAAGGTCGGCTTCCAGTCTGATCAGGAAGAAGCGATTGAGGAACAATCACTCATTGA
TTCACTAAGCAGCTACTTCAAACCAGAATTTTTGAACCGTTTTGACAGCATCATTCAGTTTGAATCATTAGACAGAGATG
ATTTAGTGAAGATTGTTGATCTTCTTCTCAATGAGCTGTCAGAGCAATTAAAAGAGCAGAATTTAACAGTCCATGTCACA
AATGAAGCGAAAGAAAAAATCGCAGAGCTTGGATATCACCCTGCATTTGGCGCTCGTCCACTTCGAAGAACCATCCAAGA
GCACGTTGAAGACCAAATGACGGAGATCCTGCTTGAAGAGGAGCAGCTTTCTGGATTTACTGTGGATGTTGAACATGACG
AAATCGTCGTAAAAAAAGGATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(253-353)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(610-687)

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

AAA domain (Cdc48 subfamily) (AAA_2)

(437-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

56.64

100

0.597
  clpE Streptococcus mutans UA159

56.199

100

0.596
  clpE Streptococcus pneumoniae Rx1

55.525

100

0.574
  clpE Streptococcus pneumoniae D39

55.525

100

0.574
  clpE Streptococcus pneumoniae R6

55.525

100

0.574
  clpE Streptococcus pneumoniae TIGR4

55.525

100

0.574
  clpC Bacillus subtilis subsp. subtilis str. 168

53.433

95.714

0.511
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.484

90.857

0.431
  clpC Streptococcus thermophilus LMD-9

45.975

92.286

0.424
  clpC Streptococcus thermophilus LMG 18311

45.82

92.286

0.423
  clpC Streptococcus pneumoniae TIGR4

44.513

92.429

0.411
  clpC Streptococcus pneumoniae Rx1

44.704

91.714

0.41
  clpC Streptococcus pneumoniae D39

44.704

91.714

0.41
  clpC Streptococcus mutans UA159

44.15

91.571

0.404

Multiple sequence alignment