Detailed information NTG0204967

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: BLL65_RS02340
• Genome accession: NZ_CP018007
• Coordinates: 468593..469756 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain sx01604
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 463593..474756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BLL65_RS02320 (BLL65_02300)	tuaH	464033..465229 (+)	1197	WP_032876154.1	teichuronic acid biosynthesis protein TuaH	-
BLL65_RS02325 (BLL65_02305)	-	465362..466438 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
BLL65_RS02330 (BLL65_02310)	-	466537..467718 (-)	1182	WP_032876157.1	LCP family protein	-
BLL65_RS02335 (BLL65_02315)	-	467723..468370 (-)	648	WP_007614107.1	YigZ family protein	-
BLL65_RS02340 (BLL65_02320)	degS	468593..469756 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
BLL65_RS02345 (BLL65_02325)	degU	469833..470522 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
BLL65_RS02350 (BLL65_02330)	-	470620..471468 (+)	849	WP_032876160.1	DegV family protein	-
BLL65_RS02355 (BLL65_02335)	comFA	471577..472962 (+)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
BLL65_RS02360 (BLL65_02340)	-	473020..473304 (+)	285	WP_003151389.1	late competence development ComFB family protein	-
BLL65_RS02365 (BLL65_02345)	comFC	473310..473999 (+)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
BLL65_RS02370 (BLL65_02350)	-	474073..474492 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=204967 BLL65_RS02340 WP_007407484.1 468593..469756(+) (degS) [Bacillus velezensis strain sx01604]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=204967 BLL65_RS02340 WP_007407484.1 468593..469756(+) (degS) [Bacillus velezensis strain sx01604]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951