Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   NCTC11637_01047 Genome accession   LS483488
Coordinates   1051630..1053414 (+) Length   594 a.a.
NCBI ID   SQJ05685.1    Uniprot ID   -
Organism   Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1046630..1058414
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NCTC11637_01042 motB 1047402..1048169 (+) 768 SQJ05670.1 Flagellar motor rotation protein -
  NCTC11637_01043 - 1048166..1048612 (+) 447 SQJ05671.1 Uncharacterised protein -
  NCTC11637_01044 opuCC 1048681..1050342 (+) 1662 SQJ05672.1 ABC transporter permease; betaine/proline/choline transporter; membrane protein -
  NCTC11637_01045 thiQ 1050344..1050985 (+) 642 SQJ05673.1 osmoprotection ATP-binding protein -
  NCTC11637_01046 - 1051168..1051629 (+) 462 SQJ05675.1 Uncharacterised protein -
  NCTC11637_01047 uvrC 1051630..1053414 (+) 1785 SQJ05685.1 excinuclease ABC subunit C Machinery gene
  NCTC11637_01048 hom 1053425..1054690 (+) 1266 SQJ05686.1 homoserine dehydrogenase -
  NCTC11637_01049 - 1054691..1055035 (+) 345 SQJ05689.1 endonuclease like protein -
  NCTC11637_01050 trxA_2 1055124..1055444 (+) 321 SQJ05916.1 thioredoxin -
  NCTC11637_01051 trxB 1055450..1056385 (+) 936 SQJ05990.1 thioredoxin reductase -
  NCTC11637_01052 lex1 1056593..1057414 (+) 822 SQJ05999.1 lipooligosaccharide 5G8 epitope biosynthesis-associated protein -
  NCTC11637_01053 - 1057633..1057881 (-) 249 SQJ06000.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68551.70 Da        Isoelectric Point: 9.5288

>NTDB_id=20404 NCTC11637_01047 SQJ05685.1 1051630..1053414(+) (uvrC) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYSKIAKECLEMIENKDKLIKELELKMECLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSTFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRGQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTANDTFKLLPSDKHLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGNFEAIEKASDQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=20404 NCTC11637_01047 SQJ05685.1 1051630..1053414(+) (uvrC) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAACAGCAGCGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ACCATCGCGCCAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAATGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGTGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGTGCAAGCAATAAAGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAACGTTTGAAAAAATCCACTCTCTCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAGCGCTTAAAGAATTGCAAGAATTTATCTCCCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAGTGCATGCCTTATAGGGTGGAAATTTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAATGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATCGATGGAGGGAGGGGGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAACGATACTTTTAAATTGCTCCCTAGCGACAAACACTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGTGTGAAAAAATTATTGGATTATTTTGGGAATTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.801

100

0.968

Multiple sequence alignment