Detailed information NTG0020400

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: NCTC11637_00417
• Genome accession: LS483488
• Coordinates: 417551..418489 (-)
• Length: 312 a.a.
• NCBI ID: SQJ03300.1
• Uniprot ID: -
• Organism: Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	412530..420335	417551..418489	within	0

Gene organization within MGE regions

Location: 412530..420335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NCTC11637_00407	ISHa1675 tnpB_2	412530..413813 (-)	1284	SQJ03287.1	ISHa1675 transposase B	-
NCTC11637_00408	tnpA_2	413883..414311 (+)	429	SQJ03288.1	transposase	-
NCTC11637_00409	-	414398..414682 (-)	285	SQJ03289.1	membrane protein	-
NCTC11637_00410	-	414689..414955 (-)	267	SQJ03290.1	membrane protein	-
NCTC11637_00411	-	414956..415246 (-)	291	SQJ03291.1	Uncharacterised protein	-
NCTC11637_00412	-	415243..415698 (-)	456	SQJ03292.1	mobilization protein	-
NCTC11637_00413	-	415695..416636 (-)	942	SQJ03293.1	VirB11 type IV secretion ATPase	-
NCTC11637_00414	-	416636..416935 (-)	300	SQJ03294.1	Uncharacterised protein	-
NCTC11637_00415	-	416932..417195 (-)	264	SQJ03296.1	Uncharacterised protein	-
NCTC11637_00416	-	417185..417481 (-)	297	SQJ03298.1	Uncharacterised protein	-
NCTC11637_00417	comB10	417551..418489 (-)	939	SQJ03300.1	VirB10 type IV secretion protein	Machinery gene
NCTC11637_00418	tnpA_3	418554..418982 (-)	429	SQJ03302.1	transposase	-
NCTC11637_00419	ISHa1675 tnpB_3	419052..420335 (+)	1284	SQJ03304.1	ISHa1675 transposase B	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35040.13 Da
• Isoelectric Point: 10.2618

>NTDB_id=20400 NCTC11637_00417 SQJ03300.1 417551..418489(-) (comB10) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
MGFLLGWFKTKPTVASNPSNYNTANEEEKTRLVILASRISSQKETQPPTSIKNSVSNTRSKEKQELEKEYGSSGFKNFKR
KNIASSENKLLRTITADRMIPAILITPISSEIGGSKIVAQVESDIYATMGRAVLIPKGSRAIGYYNSNNKIGEYRLEIAW
NRIITPQGVNIILSDARGADVKGYNGMIGTLHNKYWERYGIPLSLSTLSNGLLIGLTSGLTEAMKNKRGGFNQNYFGDYM
MMQMTRQTGISLNNIIAQIMRDQIRIKPIITIREGSHIFISPNTDIWFPIPKNNEVLAKFFNEEKEQNNDTK

Nucleotide

• Length: 939 bp

>NTDB_id=20400 NCTC11637_00417 SQJ03300.1 417551..418489(-) (comB10) [Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093 strain NCTC 11637]
TTGGGATTTCTGCTTGGGTGGTTTAAAACCAAACCTACTGTTGCCTCCAATCCTTCCAACTACAATACCGCTAACGAAGA
AGAAAAAACCCGTCTTGTGATTTTAGCGTCTCGTATTAGCAGCCAAAAAGAAACACAGCCTCCAACCTCTATAAAAAATA
GTGTTTCTAACACAAGATCCAAAGAAAAACAAGAACTTGAAAAAGAATACGGCTCTAGCGGTTTTAAAAATTTTAAAAGA
AAAAATATAGCGAGCAGTGAAAACAAACTTTTGAGAACGATTACGGCTGACAGAATGATCCCAGCCATTCTGATCACTCC
TATTAGTAGTGAAATAGGGGGGAGTAAGATAGTCGCTCAAGTGGAGAGTGATATATACGCAACGATGGGTAGAGCGGTTT
TAATCCCTAAAGGGAGTAGAGCCATAGGCTATTACAACTCTAATAACAAAATAGGCGAATACCGCTTAGAAATTGCTTGG
AATAGGATAATCACGCCACAAGGAGTCAATATCATACTAAGCGATGCTAGGGGAGCTGATGTCAAGGGCTATAACGGCAT
GATAGGCACACTCCATAACAAATATTGGGAACGCTATGGTATTCCTTTATCCTTAAGCACCTTGTCAAACGGGCTACTCA
TAGGTCTTACTAGCGGTCTTACCGAAGCGATGAAAAACAAAAGGGGTGGTTTTAACCAAAACTATTTTGGAGATTACATG
ATGATGCAAATGACGAGGCAAACTGGTATCAGCCTAAATAATATTATCGCTCAAATCATGCGAGATCAAATCAGGATTAA
GCCCATTATCACTATTAGAGAGGGAAGCCATATTTTTATCAGTCCTAATACGGATATTTGGTTTCCTATCCCTAAAAACA
ATGAAGTCTTAGCGAAATTTTTTAATGAAGAAAAGGAACAAAACAATGATACAAAATAG

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (93-288)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	54.795	93.59	0.513