Detailed information NTG0020372

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SMA_2088
• Genome accession: HE613569
• Coordinates: 2029217..2031658 (-)
• Length: 813 a.a.
• NCBI ID: CCF03379.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2024217..2036658

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_2084	-	2025063..2025890 (+)	828	CCF03375.1	Hypothetical protein	-
SMA_2085	-	2025920..2027194 (+)	1275	CCF03376.1	putative toxic anion resistance protein	-
SMA_2086	hslO	2027307..2028173 (+)	867	CCF03377.1	Chaperonin (heat shock protein 33)	-
SMA_2087	dus1	2028166..2029143 (+)	978	CCF03378.1	tRNA dihydrouridine synthase 1	-
SMA_2088	clpC	2029217..2031658 (-)	2442	CCF03379.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
SMA_2089	ctsR	2031655..2032116 (-)	462	CCF03380.1	Transcriptional regulator CtsR	-
SMA_2090	-	2032506..2032709 (+)	204	CCF03381.1	Hypothetical protein	-
SMA_2091	-	2032826..2033290 (+)	465	CCF03382.1	Small multidrug export protein	-
SMA_2092	tsf	2033428..2034465 (-)	1038	CCF03383.1	Translation elongation factor Ts	-
SMA_2093	rpsB	2034576..2035432 (-)	857	CCF03384.1	SSU ribosomal protein S2p (SAe)	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90244.54 Da
• Isoelectric Point: 5.6473

>NTDB_id=20372 SMA_2088 CCF03379.1 2029217..2031658(-) (clpC) [Streptococcus macedonicus ACA-DC 198]
MSEYSIKMQEVFSVAQYQAARFESPYLESWHVLLAMVAIHDSVAGLTFAEYQTKIAYEEYEAAAVLAIGKSPLTDVDRVH
FVEQSKALSDVLAFAESICQVTGGNEIGTEHVLYAMLLNLDLFATRLLEVAGFKNKEDGDAARLIDLRKSLARNAGFTKE
NIKAIHELRKPKKSTMGGAFSEMLKPQSTAEDLSDFTRDLTEMARQGKLEPVIGREKEISRMVQVLSRKTKNNPVLVGEA
GVGKTALAYGLAQRIVNGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIISDIEEDGHIILFIDEVHTIMGSGSG
IDSTLDAANILKPALARGTLHMVGATTQEEYQKHLEKDAALSRRFAKITIEEPSVEDAYQILLGLKKSYEDFHNVVISDE
AVLTAVKAAHRYLTSKNLPDSAIDLLDEASATVQGLVKKEAPATLTPADKAILEGDFKLATKLLKESRKKPNRKPTAVTE
DDIMATLSRLSGIPVEKMTQADSKKYLNLEKEFHKRVIGQDSAISAISRAIRRNQAGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNVLLQV
LDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDEKTVGFGARDMAHDYEAMQKRIMEELKKTYRPEFINRIDEKVVFHN
LTQENMRDVVKIMVKPLIATLAEKDITLKFQPSALKYLAEIGYDPEMGARPLRRTLQDKVEDELSELILSGELASGNTLK
IGVSKGQLKFDIA

Nucleotide

• Length: 2442 bp

>NTDB_id=20372 SMA_2088 CCF03379.1 2029217..2031658(-) (clpC) [Streptococcus macedonicus ACA-DC 198]
ATGAGTGAGTATTCGATAAAAATGCAAGAGGTTTTCAGTGTTGCTCAATACCAAGCAGCGCGTTTTGAAAGCCCATATTT
AGAAAGTTGGCACGTCCTTTTAGCTATGGTTGCTATCCATGACTCAGTCGCAGGGCTAACATTTGCGGAATACCAAACTA
AAATTGCTTATGAAGAATATGAAGCGGCAGCTGTTTTAGCCATTGGGAAATCACCGTTAACGGATGTTGACAGAGTTCAC
TTTGTGGAACAATCTAAAGCTCTTAGTGATGTTTTAGCATTTGCTGAGTCTATTTGTCAGGTGACTGGTGGTAACGAAAT
CGGGACAGAACACGTGCTTTATGCGATGTTGTTAAACCTTGATTTATTTGCCACACGTTTGTTAGAGGTTGCTGGTTTTA
AAAACAAAGAAGACGGTGACGCTGCTCGTTTGATTGATTTGCGTAAGAGTTTGGCACGTAATGCTGGTTTTACAAAGGAA
AATATCAAAGCTATTCATGAACTTCGTAAGCCGAAAAAATCGACAATGGGCGGTGCTTTTTCTGAAATGCTGAAACCACA
GTCAACAGCGGAGGATTTGTCAGATTTCACGCGTGATTTGACAGAGATGGCACGTCAAGGAAAATTAGAACCTGTTATTG
GTCGTGAAAAAGAAATTTCTCGTATGGTGCAGGTGCTTAGCCGCAAAACGAAAAACAATCCAGTTTTAGTAGGGGAAGCT
GGTGTTGGTAAAACGGCTCTTGCTTACGGTTTGGCACAGCGAATTGTCAATGGTGCGATTCCGTATGAACTCCAAGACAT
GCGTGTTTTAGAGCTTGATATGATGAGCGTTGTGGCTGGTACGCGATTCCGTGGTGATTTTGAAGAACGCATGAACCAAA
TCATCTCAGATATTGAGGAAGACGGTCATATTATTCTATTCATTGACGAAGTGCATACGATTATGGGTTCAGGCTCTGGA
ATTGACAGCACTTTGGATGCGGCTAATATTTTAAAACCAGCACTTGCGCGTGGTACGCTTCATATGGTTGGTGCGACAAC
GCAAGAAGAATATCAAAAACATCTCGAAAAAGATGCGGCGCTTTCTCGCCGTTTTGCTAAGATTACCATTGAAGAACCAA
GTGTTGAAGATGCTTACCAAATCTTGCTTGGACTAAAGAAATCATATGAAGATTTTCATAATGTGGTGATTTCTGATGAA
GCTGTTTTAACGGCTGTCAAAGCTGCGCATCGCTATTTGACAAGTAAAAATCTTCCTGATTCAGCGATTGATTTGCTTGA
TGAAGCAAGTGCAACGGTTCAAGGTTTGGTGAAAAAAGAAGCGCCAGCTACTTTGACACCTGCTGATAAAGCTATTTTGG
AAGGTGATTTCAAATTGGCAACGAAATTGCTGAAAGAGTCACGCAAGAAGCCAAATCGTAAACCAACTGCTGTGACAGAA
GATGATATTATGGCAACGCTCAGTCGTTTGTCAGGTATTCCTGTTGAGAAAATGACACAGGCAGATAGTAAGAAATACTT
GAACCTCGAAAAAGAATTCCATAAGCGTGTGATTGGCCAAGATTCAGCTATTTCAGCGATTAGTCGTGCTATTCGTCGTA
ATCAAGCGGGCATTCGTACAGGCAAACGTCCGATTGGCTCGTTTATGTTCTTGGGTCCAACGGGTGTTGGTAAAACAGAG
TTGGCTAAGGCACTAGCAGAATTGCTATTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTACATGGAAAA
ATTTGCGGCGAGCCGTCTTAACGGAGCTCCTCCAGGGTATGTCGGTTATGAAGAAGGTGGCGAATTGACTGAAAAAGTTC
GCAACAAACCTTATTCTGTGCTTCTATTTGATGAAATTGAAAAAGCCCACCCAGATATTTTCAATGTGCTTCTCCAAGTG
TTGGATGACGGTGTGCTGACGGATAGTCGTGGTCGTAAAGTTGATTTTTCAAACACGATTATTATCATGACATCAAATCT
TGGGGCAACCGCTTTGCGTGATGAAAAGACAGTTGGTTTTGGTGCGCGTGATATGGCTCATGATTATGAGGCAATGCAAA
AACGCATCATGGAAGAACTCAAAAAAACTTACCGACCTGAATTCATCAACCGTATTGATGAAAAAGTTGTTTTCCACAAC
TTAACTCAAGAAAATATGCGTGATGTCGTGAAAATCATGGTTAAACCATTGATTGCGACACTAGCTGAAAAAGATATTAC
GCTAAAATTCCAACCATCAGCATTGAAATATTTAGCCGAAATTGGATACGACCCAGAAATGGGAGCTCGTCCGCTCCGCC
GTACTCTGCAAGATAAAGTTGAAGATGAATTATCAGAGCTTATTCTATCAGGCGAATTGGCAAGTGGAAATACCCTTAAA
ATCGGTGTTTCTAAAGGGCAACTCAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• ATPase family associated with various cellular activities (AAA) (AAA) (235-366)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-800)

• AAA lid domain (AAA_lid_9) (374-452)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.724	99.877	0.766
clpC	Streptococcus thermophilus LMG 18311	73.374	100	0.736
clpC	Streptococcus thermophilus LMD-9	73.252	100	0.734
clpC	Streptococcus pneumoniae Rx1	67.442	100	0.678
clpC	Streptococcus pneumoniae D39	67.442	100	0.678
clpC	Streptococcus pneumoniae TIGR4	67.488	99.877	0.674
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.506
clpC	Bacillus subtilis subsp. subtilis str. 168	43.494	100	0.444