Detailed information NTG0020344

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SMA_0571
• Genome accession: HE613569
• Coordinates: 575965..578250 (-)
• Length: 761 a.a.
• NCBI ID: CCF01862.1
• Uniprot ID: -
• Organism: Streptococcus macedonicus ACA-DC 198
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 570965..583250

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMA_0568	ileS	571966..574764 (+)	2799	CCF01859.1	Isoleucyl-tRNA synthetase	-
SMA_0569	-	574864..575166 (-)	303	CCF01860.1	Hypothetical protein	-
SMA_0570	-	575237..575683 (-)	447	CCF01861.1	Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase)	-
SMA_0571	clpE	575965..578250 (-)	2286	CCF01862.1	ATP-dependent Clp protease, ATP-binding subunit ClpE	Regulator
SMA_0572	-	578392..578943 (-)	552	CCF01863.1	Hypothetical protein	-
SMA_0573	-	578946..579110 (-)	165	Protein_572	Hypothetical protein	-
SMA_0574	argF	579484..580464 (+)	981	CCF01865.1	Ornithine carbamoyltransferase	-
SMA_0575	-	580600..580830 (+)	231	CCF01866.1	Hypothetical protein	-
SMA_0576	glnP	581084..581770 (+)	687	CCF01867.1	ABC transporter membrane-spanning permease-glutamine transport	-
SMA_0577	-	581770..582504 (+)	735	CCF01868.1	Glutamine transport ATP-binding protein GlnQ	-

Sequence

Protein

• Length: 761 a.a.
• Molecular weight: 85008.85 Da
• Isoelectric Point: 4.7429

>NTDB_id=20344 SMA_0571 CCF01862.1 575965..578250(-) (clpE) [Streptococcus macedonicus ACA-DC 198]
MLCQNCHLNESTIHLYTNVNGQQKQIDLCQNCYQIMKTDPNNTILSGLRDATASFTQNQSTGMNPFDDFFSNLNNFHAFG
GQDFQNTPPTQSGGGNNGGNNNNYRPNGAASQQQQKGLLEEFGINVTDIARRGDIDPVIGRDAEIIRVIEILNRRTKNNP
VLIGEPGVGKTAVVEGLAQKIIDGDVPQKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRERKDVILFIDEIHEI
VGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDPALERRMQPVKVNEPSVEETITILRGIQKKYEDYHHV
KYSDDAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPQEIDKRLAEAENLKTQATREEDYERAAYFRDQI
AKYKEMQQQTINEDDIPVITEKTIEAIVEEKTNIPVGDLKEKEQSQLINLADDLKTHVIGQDDAVDKIAKAIRRNRVGLG
TPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYS
LILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSNYFSP
EFMNRFDGIIEFKALSKDNLFQIVNLMLDDVNKRLATNDIHLEVTDKVKEKLVELGYDPKMGARPLRRTIQDHIEDAITD
FYLENPSEKDLKAAMTSNDKIIIKSDKKVEKEETTVSAESE

Nucleotide

• Length: 2286 bp

>NTDB_id=20344 SMA_0571 CCF01862.1 575965..578250(-) (clpE) [Streptococcus macedonicus ACA-DC 198]
ATGCTCTGTCAAAATTGTCATTTAAACGAATCAACAATTCATCTTTATACAAATGTCAATGGTCAGCAAAAGCAAATTGA
TTTGTGCCAAAACTGCTATCAAATCATGAAAACTGACCCTAACAATACTATTTTAAGTGGTTTAAGAGATGCAACAGCTT
CTTTCACACAAAATCAATCTACTGGTATGAATCCTTTTGATGATTTCTTCAGTAATTTGAATAATTTCCACGCATTCGGT
GGACAAGATTTCCAAAATACGCCTCCAACACAATCAGGTGGTGGAAATAACGGCGGCAATAATAACAATTATCGTCCAAA
CGGCGCAGCTAGCCAACAACAACAAAAAGGTTTGCTAGAAGAATTTGGTATCAACGTTACTGATATTGCTCGTCGCGGTG
ACATCGACCCTGTCATTGGGCGTGATGCCGAAATCATTCGTGTGATTGAAATTCTTAACCGTCGTACAAAAAATAATCCT
GTTCTTATTGGTGAACCTGGGGTTGGTAAAACAGCCGTTGTTGAAGGATTAGCTCAAAAAATCATAGATGGTGACGTTCC
ACAAAAACTTCAAAATAAAGAAGTTATTCGTCTTGATGTCGTTAGCCTTGTACAAGGAACAGGTATTCGTGGTCAATTTG
AAGAACGTATGCAAAAACTCATGGAAGAAATCCGTGAACGTAAGGACGTTATTCTCTTCATTGACGAAATTCACGAAATT
GTCGGTGCTGGTTCTGCAGGCGACGGTAACATGGACGCTGGTAATATTTTAAAACCAGCACTTGCTCGTGGTGAACTTCA
ATTAGTTGGTGCTACGACACTCAATGAATACCGCATTATTGAAAAAGATCCAGCACTTGAACGCCGTATGCAACCTGTCA
AAGTTAATGAACCAAGCGTGGAAGAAACGATTACGATTCTTCGTGGTATTCAAAAGAAATACGAAGATTATCATCATGTC
AAATACAGCGATGATGCAATTGAGGCTGCCGCAAATCTTTCTAACCGTTACATTCAAGACCGCTTCCTCCCAGATAAAGC
CATTGATTTGCTAGACGAAGCTGGTTCTAAGATGAATTTAACCCTTAACTTTGTTGACCCACAAGAAATCGACAAGCGTT
TAGCGGAAGCTGAAAACCTAAAAACACAAGCTACTCGCGAGGAAGATTATGAACGCGCAGCTTATTTCCGTGACCAAATC
GCTAAATACAAGGAAATGCAACAACAAACAATCAACGAAGACGATATTCCAGTTATTACTGAAAAGACTATCGAAGCTAT
CGTTGAAGAAAAAACTAACATTCCTGTTGGTGATTTGAAAGAAAAGGAACAATCACAATTAATCAATCTCGCTGATGATT
TGAAAACACACGTCATTGGTCAAGATGATGCCGTTGACAAAATTGCCAAAGCCATTCGTCGTAACCGTGTCGGTCTCGGT
ACACCAAATCGTCCAATCGGTTCATTCCTCTTTGTTGGACCAACTGGTGTTGGTAAAACAGAACTTTCTAAACAATTAGC
GATTGAACTTTTCGGCTCAGCTGACAACATGATTCGTTTCGATATGTCTGAATACATGGAAAAACATGCGGTCGCTAAAC
TTGTTGGAGCACCTCCAGGATACGTTGGTTACGAAGAAGCTGGTCAATTGACAGAAAAAGTTCGCCGTAATCCATACTCA
CTCATCCTTCTTGACGAAGTTGAAAAAGCGCATCCTGATGTTATGCATATGTTCTTGCAAGTTCTTGATGACGGTCGTTT
GACTGACGGTCAAGGTCGTACAGTAAGCTTCAAAGATACTATTATTATCATGACTTCTAATGCTGGTACTGGTAAAACAG
AAGCTTCAGTTGGTTTCGGTGCTGCTCGTGAAGGACGTACAAATTCTGTCCTTGGTGAACTTAGCAACTACTTCAGCCCT
GAATTCATGAACCGTTTCGACGGTATTATCGAATTTAAGGCTCTTAGCAAGGACAATCTTTTCCAAATTGTTAACCTTAT
GCTTGACGATGTCAATAAACGTCTAGCAACTAACGATATTCACCTCGAAGTCACTGATAAGGTAAAAGAAAAATTAGTTG
AACTTGGCTACGATCCTAAAATGGGAGCTCGTCCATTACGTCGTACTATCCAAGACCACATTGAAGATGCCATTACAGAC
TTCTATCTTGAAAATCCAAGCGAAAAAGATTTGAAAGCTGCTATGACAAGCAATGATAAAATTATCATCAAATCTGATAA
AAAGGTTGAAAAAGAAGAAACAACCGTTTCAGCAGAATCAGAATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (484-647)

• ATPase family associated with various cellular activities (AAA) (AAA) (161-289)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (655-729)

• AAA lid domain (AAA_lid_9) (299-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.973	98.817	0.84
clpE	Streptococcus pneumoniae Rx1	83.134	98.949	0.823
clpE	Streptococcus pneumoniae D39	83.134	98.949	0.823
clpE	Streptococcus pneumoniae R6	83.134	98.949	0.823
clpE	Streptococcus pneumoniae TIGR4	83.134	98.949	0.823
clpC	Lactococcus lactis subsp. cremoris KW2	76.026	99.212	0.754
clpC	Bacillus subtilis subsp. subtilis str. 168	51.657	87.254	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.48	82.129	0.398
clpC	Streptococcus pneumoniae Rx1	46.552	83.837	0.39
clpC	Streptococcus pneumoniae D39	46.552	83.837	0.39
clpC	Streptococcus pneumoniae TIGR4	46.395	83.837	0.389
clpC	Streptococcus mutans UA159	47.658	81.34	0.388
clpC	Streptococcus thermophilus LMD-9	46.527	81.34	0.378
clpC	Streptococcus thermophilus LMG 18311	46.216	81.603	0.377