Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   Spy49_1387c Genome accession   CP000829
Coordinates   1385949..1386731 (-) Length   260 a.a.
NCBI ID   ACI61665.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1380949..1391731
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1382c gatB 1381046..1382485 (-) 1440 ACI61660.1 Aspartyl-tRNA(Asn) amidotransferase subunit B Glutamyl-tRNA(Gln) amidotransferase subunit B -
  Spy49_1383c gatA 1382485..1383951 (-) 1467 ACI61661.1 Aspartyl-tRNA(Asn) amidotransferase subunit A -
  Spy49_1384c gatC 1383951..1384253 (-) 303 ACI61662.1 Aspartyl-tRNA(Asn) amidotransferase subunit C -
  Spy49_1385c - 1384485..1384733 (-) 249 ACI61663.1 Pyruvate,phosphate dikinase -
  Spy49_1386c - 1385248..1385802 (-) 555 ACI61664.1 Nicotinamidase -
  Spy49_1387c codY 1385949..1386731 (-) 783 ACI61665.1 GTP-sensing transcriptional pleiotropic repressor codY Regulator
  Spy49_1388c - 1386949..1388130 (-) 1182 ACI61666.1 Aspartate aminotransferase -
  Spy49_1389 - 1388395..1388847 (+) 453 ACI61667.1 Conserved hypothetical protein -
  Spy49_1390c - 1388970..1390358 (-) 1389 ACI61668.1 hypothetical protein -
  Spy49_1391 asnB 1390430..1391395 (+) 966 ACI61669.1 Putative L-asparaginase -

Sequence

Protein


Download         Length: 260 a.a.        Molecular weight: 28633.76 Da        Isoelectric Point: 4.5611

>NTDB_id=20289 Spy49_1387c ACI61665.1 1385949..1386731(-) (codY) [Streptococcus pyogenes NZ131]
MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNACIINGGGTLLGYAMKYKTNTDRVEEFFEAKQFPDTYV
KAASRVYDTEANLSVENELTIFPVESKDTYPGGLTTIAPIYGGGMRLGSLIIWRNDNEFSDDDLILVEISSTVVGIQLLN
LQTENLEDTIRKQTAVNMAINTLSYSEMKAVAAILGELDGNEGRLTASVIADRIGITRSVIVNALRKLESAGIIESRSLG
MKGTYLKVINEGIFAKLKEF

Nucleotide


Download         Length: 783 bp        

>NTDB_id=20289 Spy49_1387c ACI61665.1 1385949..1386731(-) (codY) [Streptococcus pyogenes NZ131]
ATGCCTAACTTATTAGAAAAAACTCGTAAAATCACATCTATTTTGCAGCGTTCCGTAGATAGCCTAGAAACAGAATTACC
GTATAACACAATGGCATCTCGCCTAGCAGATATCATTGACTGCAATGCTTGTATTATCAATGGCGGCGGCACACTGCTTG
GTTATGCCATGAAATATAAAACTAACACTGATCGTGTTGAGGAATTTTTTGAAGCTAAACAATTTCCAGATACTTATGTA
AAGGCTGCTAGCCGAGTTTACGATACAGAAGCTAACCTTTCTGTCGAAAATGAGTTGACTATATTCCCTGTTGAGTCTAA
AGACACTTATCCAGGAGGTCTAACGACTATTGCGCCGATTTATGGTGGAGGGATGCGCCTTGGATCACTCATTATCTGGC
GTAATGACAATGAGTTTAGTGATGATGATTTGATTTTGGTTGAGATCTCAAGTACTGTTGTGGGGATTCAATTATTAAAT
CTTCAGACAGAAAACTTAGAAGACACCATCCGTAAACAAACAGCGGTCAACATGGCAATTAATACGCTTTCTTATTCAGA
AATGAAAGCTGTTGCAGCAATTCTTGGAGAGTTAGATGGTAATGAAGGACGATTGACAGCTTCTGTTATTGCTGATCGTA
TTGGTATTACCCGTTCTGTTATTGTCAATGCTCTGCGTAAACTAGAAAGTGCAGGGATTATTGAAAGTCGTTCTCTTGGT
ATGAAAGGGACATACCTCAAAGTTATCAACGAAGGTATTTTTGCTAAATTAAAAGAATTTTAA

Domains

Predicted by InterProScan.

CodY helix-turn-helix domain (HTH_CodY)

(202-260)

CodY GAF-like domain (CodY)

(3-182)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Lactococcus lactis subsp. lactis strain DGCC12653

66.148

98.846

0.654
  codY Bacillus subtilis subsp. subtilis str. 168

51.373

98.077

0.504

Multiple sequence alignment