Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   BK055_RS06380 Genome accession   NZ_CP017775
Coordinates   1226708..1227364 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain 9912D     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1221708..1232364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BK055_RS06355 (BK055_06355) oppF 1222248..1223165 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  BK055_RS06360 (BK055_06360) - 1223272..1224450 (+) 1179 WP_079979752.1 putative glycoside hydrolase -
  BK055_RS06365 (BK055_06365) - 1224568..1225146 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  BK055_RS06370 (BK055_06370) spx 1225325..1225720 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  BK055_RS06375 (BK055_06375) - 1225776..1226432 (-) 657 WP_014417421.1 TerC family protein -
  BK055_RS06380 (BK055_06380) mecA 1226708..1227364 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  BK055_RS06385 (BK055_06385) - 1227515..1228675 (+) 1161 WP_071181701.1 competence protein CoiA family protein -
  BK055_RS06390 (BK055_06390) pepF 1228903..1230732 (+) 1830 WP_106067880.1 oligoendopeptidase F Regulator
  BK055_RS22035 - 1230770..1230937 (-) 168 WP_003155026.1 hypothetical protein -
  BK055_RS06395 (BK055_06395) spxH 1231223..1232125 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=202799 BK055_RS06380 WP_003155032.1 1226708..1227364(+) (mecA) [Bacillus velezensis strain 9912D]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=202799 BK055_RS06380 WP_003155032.1 1226708..1227364(+) (mecA) [Bacillus velezensis strain 9912D]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment