Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FORC61_RS06255 Genome accession   NZ_CP022607
Coordinates   1247508..1249517 (+) Length   669 a.a.
NCBI ID   WP_000516267.1    Uniprot ID   -
Organism   Staphylococcus aureus strain FORC_061     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1242508..1254517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FORC61_RS06240 (FORC61_1126) - 1243691..1244056 (+) 366 WP_000282386.1 RicAFT regulatory complex protein RicA family protein -
  FORC61_RS06245 (FORC61_1127) thiW 1244083..1244574 (+) 492 WP_000842277.1 energy coupling factor transporter S component ThiW -
  FORC61_RS06250 (FORC61_1128) hexA 1244877..1247495 (+) 2619 WP_000073344.1 DNA mismatch repair protein MutS Machinery gene
  FORC61_RS06255 (FORC61_1129) hexB 1247508..1249517 (+) 2010 WP_000516267.1 DNA mismatch repair endonuclease MutL Machinery gene
  FORC61_RS06260 (FORC61_1130) - 1249523..1250065 (+) 543 WP_001792629.1 glycerol-3-phosphate responsive antiterminator -
  FORC61_RS06265 (FORC61_1131) - 1250532..1251350 (+) 819 WP_001103743.1 MIP/aquaporin family protein -
  FORC61_RS06270 (FORC61_1132) glpK 1251479..1252975 (+) 1497 WP_000417369.1 glycerol kinase GlpK -

Sequence

Protein


Download         Length: 669 a.a.        Molecular weight: 76886.08 Da        Isoelectric Point: 5.0124

>NTDB_id=201897 FORC61_RS06255 WP_000516267.1 1247508..1249517(+) (hexB) [Staphylococcus aureus strain FORC_061]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQSTENNQEKTFSSEESNSKPFMEENQNDEIVIKEDSYNPFV
TKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDDTTVQNYENKASDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKLFKRVM

Nucleotide


Download         Length: 2010 bp        

>NTDB_id=201897 FORC61_RS06255 WP_000516267.1 1247508..1249517(+) (hexB) [Staphylococcus aureus strain FORC_061]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGGCATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAACAGAATGGCAATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGTTAAATAAAGCGAT
TTTAGAAGGCTACCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCGATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATACCAATTGATTGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCGAAAAAAAATAAAGTATTACA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAGCACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACAGTAAGCCATTTATGGAAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCATATAATCCATTCGTA
ACGAAAACATCTGAAAGTTTAATAGCTGATGATGAATCTTCTGGTTATAATAATACACGTGAAAAAGATGAAGACTACTT
CAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACATTTGATTCAAATGATGATACAACTGTGCAAAATTATGAGA
ATAAAGCGTCTGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGACAAGTACATGGAACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAGGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAAGATGAACAATTAGTCATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATTAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTAGATATCAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCCATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATAATCATTAATTTTTCAAAATACGAATTAGAAAAATTATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)

MutL C terminal dimerisation domain (MutL_C)

(483-625)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

42.121

100

0.428