Detailed information NTG0201780

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB525_RS09620
• Genome accession: NZ_CP017685
• Coordinates: 1896616..1897659 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN007835
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1891616..1902659

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB525_RS09590 (AB525_09390)	-	1892037..1893284 (-)	1248	WP_000656302.1	aminopeptidase	-
AB525_RS09595 (AB525_09395)	-	1893296..1893496 (-)	201	WP_000180459.1	DUF1128 family protein	-
AB525_RS09600 (AB525_09400)	-	1893643..1894107 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
AB525_RS09605 (AB525_09405)	-	1894114..1894389 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB525_RS09610 (AB525_09410)	-	1894667..1895884 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
AB525_RS09615 (AB525_09415)	vraR	1895997..1896626 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB525_RS09620 (AB525_09420)	vraS	1896616..1897659 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB525_RS09625 (AB525_09425)	liaF	1897656..1898357 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB525_RS09630 (AB525_09430)	-	1898372..1898758 (-)	387	WP_001110184.1	hypothetical protein	-
AB525_RS09635 (AB525_09435)	map	1898975..1899733 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
AB525_RS09645 (AB525_09440)	-	1900264..1901250 (+)	987	WP_000999713.1	FUSC family protein	-
AB525_RS09650 (AB525_09445)	-	1901428..1901841 (-)	414	WP_001622129.1	hypothetical protein	-
AB525_RS09655 (AB525_09450)	-	1901870..1901979 (-)	110	Protein_1791	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=201780 AB525_RS09620 WP_001017131.1 1896616..1897659(-) (vraS) [Staphylococcus aureus strain CFSAN007835]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=201780 AB525_RS09620 WP_001017131.1 1896616..1897659(-) (vraS) [Staphylococcus aureus strain CFSAN007835]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1