Detailed information NTG0201738

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB520_RS10215
• Genome accession: NZ_CP017684
• Coordinates: 2005495..2006538 (-)
• Length: 347 a.a.
• NCBI ID: WP_099119663.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain CFSAN007847
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2000495..2011538

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB520_RS10185 (AB520_09970)	-	2000916..2002172 (-)	1257	WP_001793983.1	aminopeptidase	-
AB520_RS10190 (AB520_09975)	-	2002175..2002375 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB520_RS10195 (AB520_09980)	-	2002522..2002986 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
AB520_RS10200 (AB520_09985)	-	2002993..2003268 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB520_RS10205 (AB520_09990)	-	2003546..2004763 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
AB520_RS10210 (AB520_09995)	vraR	2004876..2005505 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB520_RS10215 (AB520_10000)	vraS	2005495..2006538 (-)	1044	WP_099119663.1	sensor histidine kinase	Regulator
AB520_RS10220 (AB520_10005)	liaF	2006535..2007236 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB520_RS10225 (AB520_10010)	-	2007251..2007637 (-)	387	WP_001110178.1	hypothetical protein	-
AB520_RS10230 (AB520_10015)	map	2007854..2008612 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB520_RS10245 (AB520_10020)	-	2009312..2010298 (+)	987	WP_001014424.1	FUSC family protein	-
AB520_RS10250 (AB520_10025)	-	2010487..2010900 (-)	414	WP_001643743.1	hypothetical protein	-
AB520_RS10255 (AB520_10030)	-	2010929..2011039 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40063.57 Da
• Isoelectric Point: 6.1140

>NTDB_id=201738 AB520_RS10215 WP_099119663.1 2005495..2006538(-) (vraS) [Staphylococcus aureus strain CFSAN007847]
MNRYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=201738 AB520_RS10215 WP_099119663.1 2005495..2006538(-) (vraS) [Staphylococcus aureus strain CFSAN007847]
ATGAACCGCTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997