Detailed information NTG0201695

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB526_RS09905
• Genome accession: NZ_CP017682
• Coordinates: 1947905..1948948 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain CFSAN007850
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1942905..1953948

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB526_RS09875 (AB526_09715)	-	1943326..1944582 (-)	1257	WP_001795108.1	aminopeptidase	-
AB526_RS09880 (AB526_09720)	-	1944585..1944785 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB526_RS09885 (AB526_09725)	-	1944932..1945396 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB526_RS09890 (AB526_09730)	-	1945403..1945678 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB526_RS09895 (AB526_09735)	-	1945956..1947173 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AB526_RS09900 (AB526_09740)	vraR	1947286..1947915 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB526_RS09905 (AB526_09745)	vraS	1947905..1948948 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB526_RS09910 (AB526_09750)	liaF	1948945..1949646 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB526_RS09915 (AB526_09755)	-	1949661..1950047 (-)	387	WP_001110179.1	hypothetical protein	-
AB526_RS09920 (AB526_09760)	map	1950264..1951022 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB526_RS09930 (AB526_09770)	-	1951553..1952539 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
AB526_RS09935 (AB526_09775)	-	1952970..1953383 (-)	414	WP_001557448.1	hypothetical protein	-
AB526_RS09940 (AB526_09780)	-	1953412..1953522 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=201695 AB526_RS09905 WP_001017131.1 1947905..1948948(-) (vraS) [Staphylococcus aureus strain CFSAN007850]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=201695 AB526_RS09905 WP_001017131.1 1947905..1948948(-) (vraS) [Staphylococcus aureus strain CFSAN007850]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1