Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   CG712_RS06365 Genome accession   NZ_CP022547
Coordinates   1208638..1210581 (+) Length   647 a.a.
NCBI ID   WP_014607839.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain B59671     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1203638..1215581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CG712_RS06335 (CG712_06370) argR 1203837..1204265 (+) 429 WP_024704313.1 arginine repressor -
  CG712_RS06340 (CG712_06375) - 1204265..1204624 (+) 360 WP_084825706.1 YlbF family regulator -
  CG712_RS06345 (CG712_06380) hexA 1204617..1207175 (+) 2559 WP_096811767.1 DNA mismatch repair protein MutS Machinery gene
  CG712_RS10740 (CG712_06385) - 1207209..1207604 (-) 396 Protein_1211 DUF3021 domain-containing protein -
  CG712_RS06355 (CG712_06390) - 1207667..1208057 (-) 391 Protein_1212 LytTR family DNA-binding domain-containing protein -
  CG712_RS06360 (CG712_06395) - 1208281..1208586 (+) 306 WP_002949050.1 hypothetical protein -
  CG712_RS06365 (CG712_06400) hexB 1208638..1210581 (+) 1944 WP_014607839.1 DNA mismatch repair endonuclease MutL Machinery gene
  CG712_RS06370 (CG712_06405) - 1210711..1210932 (+) 222 WP_096811769.1 hypothetical protein -
  CG712_RS06375 (CG712_06410) ruvA 1211084..1211674 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA Machinery gene
  CG712_RS06380 (CG712_06415) - 1211681..1212235 (+) 555 Protein_1217 DNA-3-methyladenine glycosylase I -
  CG712_RS06385 (CG712_06420) cinA 1212331..1213602 (+) 1272 WP_096811771.1 competence/damage-inducible protein A Machinery gene
  CG712_RS06390 (CG712_06425) recA 1213638..1214777 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  CG712_RS06395 (CG712_06430) spx 1214954..1215352 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72531.80 Da        Isoelectric Point: 5.9934

>NTDB_id=201645 CG712_RS06365 WP_014607839.1 1208638..1210581(+) (hexB) [Streptococcus thermophilus strain B59671]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQADVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEVYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALIKS
AIAQSLREQDLIPDALENLAKSSTRGATRSVQTSLPLKQTNLYYDSNRNDFFVTPETVQEDIKPLVSKSESSVSLVANKQ
QPTVKQAKRSADDSDSEHGKLDYKNKSKLKRMLENLTNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYREKIGVVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVCIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=201645 CG712_RS06365 WP_014607839.1 1208638..1210581(+) (hexB) [Streptococcus thermophilus strain B59671]
ATGCCAAAAATTATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGTGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACTATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATCACAGACAATGGCGAAGGAATGGCTCAAGCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACGAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACACTTGGTTTTCGAGGTGAAGCCCTACCCTCTATAGCTTCTATTAG
TCACCTTACCATTGTGACAGCAGCGGATGGAGAAGTCTATGGGACCAAACTTGTTGCTAAAGGTGGAGAAATTGAGAGTC
AAGATCCTATTTCAACCCCAGTGGGAACAAAGATTACAGTTGAAAACTTGTTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCTGAGTTGGCTCATATTGTCGATGTTGTCAACCGTTTGAGTTTAGCCCACCCCGAAGTAGCCTT
CACCTTGCTTAATGATGGTCGTCAGTTGACACAGACATCAGGTACTGGAGACCTTCGCCAAGCTATTGCAGGGATTTATG
GCTTAACAACAGCAAAAAAAATGGTGGAAATTTCAAATTCCGACCTTGATTTTGAAGTTTCTGGTTATGTCAGTCTCCCT
GAATTAACGCGTGCTAACCGTAACTACATCACGATTCTCATTAACGGACGCTATATAAAAAACTTCCTCCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTTATGGTGGGACGCTTCCCAATTGCAGTTATTGATATTCAGATTGATCCTTATT
TGGCAGATGTCAATGTTCACCCAACAAAGCAAGAAGTACGTATCTCTAAAGAAAAGGAGCTCATGGCCCTTATCAAATCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCAAAGTCAAGTACTAGAGGTGC
AACTAGGTCAGTTCAGACGAGTCTCCCACTCAAACAAACCAATCTTTACTATGACAGTAACCGTAATGATTTCTTTGTCA
CGCCAGAGACAGTTCAAGAGGATATCAAACCTCTTGTATCAAAGTCAGAGTCTTCAGTTTCATTGGTAGCAAACAAACAG
CAACCTACTGTTAAACAGGCAAAACGTTCAGCAGATGATAGTGATAGCGAACACGGAAAACTTGACTATAAAAATAAATC
GAAATTGAAGCGCATGCTTGAAAATCTGACCAATGAGGAAACATCAACCTTTCCTGAATTGGAGTTCTTTGGTCAAATGC
ATGGAACCTACCTCTTTGCCCAAGGACAAGGTGGCCTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAAGATAGGTGTGGTTGATAGTAGTTTACAACAACTTTTGGTTCCCTATCTTTTTGAATTTTCAGG
TTCAGATTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAACCAAGTTTGCATCTATTTGGAGCCTTATGGGAATAATA
CCTTCATTCTTCGAGAGCACCCTATCTGGATGAAGGAAGAAGAAATCGAATCTGCAGTCTATGAGATGTGTGATATGCTT
CTTTTGACGAACGAAGTATCCGTCAAGACCTATCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATAAAGGC
CAATCATGCTCTTGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGTAAAAATCCCTATAATTGTCCTC
ACGGCCGTCCAGTACTTGTCAACTTTACCAAGTCTGATATGGAGAAAATGTTCCGTCGTATTCAAGAAAACCATACCAGC
CTACGTGATTTAGGAAAGTATTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(448-591)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.419

100

0.702