Detailed information NTG0201574

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB466_RS13570
• Genome accession: NZ_CP017677
• Coordinates: 2628291..2629178 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CFSAN007894
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2623291..2634178

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB466_RS13535 (AB466_13240)	-	2623310..2623402 (+)	93	WP_010956583.1	hypothetical protein	-
AB466_RS13540 (AB466_13245)	-	2623510..2624007 (-)	498	WP_031900639.1	glutathione peroxidase	-
AB466_RS13545 (AB466_13250)	-	2624017..2624277 (-)	261	WP_001791974.1	hypothetical protein	-
AB466_RS13555 (AB466_13255)	-	2624659..2624772 (-)	114	Protein_2529	hypothetical protein	-
AB466_RS13560 (AB466_13265)	-	2625431..2627431 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB466_RS13565 (AB466_13270)	-	2627428..2628183 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB466_RS13570 (AB466_13275)	braS	2628291..2629178 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB466_RS13575 (AB466_13280)	braR	2629189..2629854 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB466_RS13580 (AB466_13285)	-	2629880..2630080 (-)	201	WP_000604730.1	hypothetical protein	-
AB466_RS13585 (AB466_13295)	-	2630278..2631702 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AB466_RS14285	-	2631772..2631882 (+)	111	Protein_2536	hypothetical protein	-
AB466_RS13595 (AB466_13305)	-	2631985..2632440 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB466_RS13600 (AB466_13310)	-	2632685..2633446 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=201574 AB466_RS13570 WP_000143425.1 2628291..2629178(-) (braS) [Staphylococcus aureus strain CFSAN007894]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=201574 AB466_RS13570 WP_000143425.1 2628291..2629178(-) (braS) [Staphylococcus aureus strain CFSAN007894]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1